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Simple breath test could be used to detect ovarian cancer and related confitions

Posted Apr 04 2009 8:34pm

According to theResults From Annual Screens(published this month), screening tests for ovarian cancer fail to detect the early signs of the disease, yet positive screens often result in unnecessary surgery.

Better tests are needed and you can help to develop them - if you were diagnosed with endometriosis, PCOS, ovarian cancer or are a healthy volunteer.

All you do is breathe in a tube for a few minutes. Chemicals in the breath will be used to develop a test for early diagnostics of ovarian cancer. Ashley McKnight, the study coordinator, can be reached at (415) 342-0886.


Read more about the study here:

Location: 124 Pine St, San Anselmo, CA

O (Oprah) Magazine will feature a story about this study in their June 2009 issue.

Other Currently Recruiting Diagnostic Clinical Trials

Ovarian Screening Study (James Graham Brown Cancer Center)

Objectives:To identify women at increased risk for developing ovarian cancer; To detect ovarian cancers at an early stage; To investigate the role of tumor membrane fragments as tumor markers for early ovarian carcinoma

Clinical Trial to Screen Participants Who Are at High Genetic Risk for Ovarian Cancer (Massachusetts General Hospital)

Interventions: screening questionnaire administration ; study of high risk factors

Study of Individuals and Families at High Risk for Breast or Ovarian Cancer (National Cancer Institute, NCI)

Interventions: gene mapping, mutation analysis, questionnaire administration; biopsy, breast duct lavage, breast imaging study, magnetic resonance imaging, mammography, study of high risk factors

CA 125 Algorithm for the Early Detection of Ovarian Cancer (MD Anderson Cancer Center)

Intervention: Questionnaire

Currently Available Preventive Screening Tests  


For women with a BRCA mutation, American College if Obstetricians and Gynecologists recommends periodic screening withCA-125 testand transvaginal ultrasonography beginning between the ages of 30 and 35 years or 5-10 years earlier than the earliest age of first diagnosis of ovarian cancer in the family.


Risk-reducing salpingo-oophorectomy surgery—which removes both of the ovaries and fallopian tubes—can reduce the risk of ovarian and fallopian tube cancer by about 85% to 90% among BRCA carriers. Women who have BRCA1 or BRCA2 mutations or HNPCC mutation should be offered risk-reducing salpingo-oophorectomy by age 40/45 or when childbearing is complete. The ideal time for this surgery depends on the type of gene mutation .




85-90% of ovarian cancers occur in women without a family history. There is a 1.5% probability that a woman develops ovarian cancer by the age of 70; it’s 5% if it runs in your family ; 18 to 50% if it is in your genes. The risk is higher for obese women (BMI >30), those that have used fertility drugs, hormones, and some endometriosis medications, and it goes up with age.

Ovarian cancer hotline

Women or family members interested in volunteering for the hotline can contact Theresa Conti at or leave a message on the hotline stating their interest. Women who wish to speak with an ovarian cancer survivor can call the toll-free Ovarian Cancer Hotline at (866)-53SHARE.





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