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MTHFR…WTF?

Posted Apr 23 2009 5:25pm

AF has still not arrived.  Cycle Day 42 and counting.  Good thing we already had a consult scheduled with Dr. Yacht for Tuesday just to make sure we had a solid understanding of our protocol for the next go-around.  He said that a delayed natural cycle after a failed IVF is not normal per se but also not uncommon.  After a quick wanding and blood test, it’s been determined that my lining is still pretty thick (10mm) and my estrogen is high, so I’ve won myself a Provera prescription to bring on my period.  After that, I’ll go on BCP to make sure I’ m adequately suppressed for the June cycle.  Stims should start in late May.  The break was much needed.  I’m feeling much more emotionally ready this time than last time when we went from IVF #1 to IVF #2 with little more than a month in between.

We also got the results of my genetic testing back.  I sent an e-mail to the nurse on Monday asking if they were back so we could be sure to address them in our appointment on Tuesday.  She e-mailed back and said everything was normal except I came back positive for MTHFR, so we’d be adding Lovenox after the transfer due to a slightly elevated risk of blood clotting.  This, of course, sent me straight to the library of the University of Google School of Medicine where I freaked myself out in short order.  By the time I went to Dr. Yacht I had a whole host of questions that caused him to give me his patented slightly patronizing but at the same time weirdly comforting smirk.   Turns out, I have the relatively common and much less concerning heterozygous variety and when he tested the homocysteine levels, those were all normal, so he feels there is nothing to worry about.  The Lovenox is just a precautionary measure as quite frankly he can’t figure out why 6 high quality embryos have failed to implant and figures we’ll just cover our bases.

Sorry this is such a boring post.  Just wanted to get something up as I haven’t felt very “post-worthy” lately.  I’m cooking up a few posts in the coming days about my experience going back home for Easter this past weekend as well as other bloggy thoughts.  Thanks for bearing with me!

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