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Terfenadine

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Terfenadine - Wikipedia, the free encyclopedia
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was marketed under various brand names including Seldane in the ...

Terfenadine-associated ventricular arrhythmias and QTc interval ...
Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a ...

Pharmaceuticals: Restrictions in Use and Availability ...
The Agence du Médicament has withdrawn the antihistamine, terfenadine from the market because the risk of ventricular arrhythmias does not justify the ...

Assessment of the potential for a pharmacokinetic interaction ...
BACKGROUND: Because inhibition of the first-pass metabolism of terfenadine may be associated with fatal arrhythmia, we assessed the possibility that ...

WHO Pharmaceuticals Newsletter 2003, No. 05: REGULATORY MATTERS ...
TERFENADINE - Withdrawn due to ventricular arrhythmias ... This measure follows associations of life-threatening ventricular arrhythmias with terfenadine. ...

Mechanism of the cardiotoxic actions of terfenadine.
OBJECTIVES AND METHODS--To gain insight into possible mechanisms of and predisposing factors for torsades de pointes during terfenadine therapy, ...

WHO Pharmaceuticals Newsletter 1999, No. 05&06: Regulatory actions ...
The Ministry of Health has withdrawn from the market products containing the histamine H1-receptor antagonist, terfenadine, because of reports of a ...

Oxidation of the antihistaminic drug terfenadine in human liver ...
Microsomal oxidation of (both enantiomers of) terfenadine to 1 and 2 was markedly inhibited by gestodene, a selective mechanism-based inactivator of P- 450 ...

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Appendix A: Financial Disclosure for Members of the DHHS Panel on ...
Astemizole and terfenadine are not marketed in the United States. ... terfenadine cisapride pimozide midazolam∑ triazolam dihydroergotamine. (D.H.E. 45) ...

Diflucan Clinical Pharmacology - Fluconazole - HealthScout
Six healthy volunteers received terfenadine 60 mg BID for 15 days. ... Fluconazole did not affect terfenadine plasma concentrations. ...

Allegra D Warnings & Precautions
Reproduction and fertility studies with terfenadine in rats produced no effect on ... Oral doses of 150 and 300 mg/kg of terfenadine produced AUC values of ...

Allegra Warnings & Precautions - Fexofenadine - USA Today
The carcinogenic potential and reproductive toxicity of fexofenadine hydrochloride were assessed using terfenadine studies with adequate fexofenadine ...

Drug Interactions Associated with the Protease Inhibitors - The Body
cold and allergy (antihistamine), terfenadine, Seldane (no longer available). astemizole, Hismanal ... Hismanal (astemizole) and Seldane (terfenadine). ...

Diflucan Warnings & Precautions - Fluconazole - HealthScout
The combined use of fluconazole at doses of 400 mg or greater with terfenadine is contraindicated. (See CONTRAINDICATIONS and CLINICAL PHARMACOLOGY: Drug ...

Medications that should NOT be used with Protease - The Body
terfenadine (Seldane). astemizole (Hismanal). terfenadine (Seldane). astemizole (Hismanal). terfenadine ... terfenadine (Seldane). loratadine (Claritin) ...

Biaxin Side Effects & Drug Interactions - clarithromycin - USA Today
When clarithromycin and terfenadine were coadministered, plasma concentrations of the active acid metabolite of terfenadine were threefold higher, ...