Use of Tetracyclines as Anti-Cancer Agentsby
derivatives to be potent inhibitors of tyrosyl-DNA-phosphodiesterase (Tdp1).
Camptothecins are effective... phosphodiesterase (Tdp1) by aminoglycoside antibiotics and ribosome inhibitors. Mol Pharmacol. 2006 Jul;70(1...
Caffeine and Creativityby
gives your body energy. Phosphodiesterase is an enzyme that breaks down cyclic AMP. Caffeine blocks phosphodiesterase. So cyclic AMP stays around longer when you have caffeine in your blood, and you have more energy...