I am not an MD so cannot answer your question, directly, but I suggest you check the article, "Alcohol-induced Bone Disease," at this link: http://www.eurekalert.org/pub_releases/2005-12/ace-abd120705.php.
Leg edema from Suboxoneby
to Suboxone. My medical Doc and I noticed that when I restart the Suboxone, I get 2-3 plus pitting edema... Suboxone in preparation for surgery, I immediately lose 15 lbs and the edema goes away. My Suboxone Doc...