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Keratinocytes

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Method of Producing Immortalized Primary Human Keratinocytes for HPV Investigation, Testing of Therapeutics, and Skin Graft Gene by nih.gov Description of Invention: One of the major limitations of using cultured keratinocytes for research studies is that primary keratinocytes senesce after a few passages. Keratinocytes from specific...
No end to telomeres by Dr. Chris P. Doctor of Philosophy in human keratinocytes elicits senescence and a novel transcription profile, Mintyet al.: Transcriptional profiling of TRF2-depleted keratinocytes showed a reproducible up-regulation of several genes. … This study...
AMP-activated kinase, a target of exercise mimetics, may contribute to photoaging and cell death by Dr. Chris P. Doctor of Philosophy - and H 2 O 2 -induced apoptosis in human skin keratinocytes AMP-activated protein kinase or AMPK... that UV and H2O2 induce AMPK activation (Thr172 phosphorylation) in cultured human skin keratinocytes. UV...
Keep Your Genes On!: An Analysis of the New Estée Lauder Advanced Night Repair Synchronized Recovery Complex by Nicki Z. Patient Expert , the PER-1 gene activator will activate your keratinocyte genes at a time when they would normally be less... arise:   One, the genetic material of the keratinocyte cell, including the DNA, is protected in the nucleus...
Genetics Home Reference: epidermal nevus by nih.gov primarily of a specific cell type called a keratinocyte. One group of epidermal nevi, called keratinocytic or nonorganoid epidermal nevi, includes nevi that involve only keratinocytes. Other types of epidermal nevi involve...
Genetics Home Reference: epidermolytic hyperkeratosis by nih.gov instructions for making proteins called keratin 1 and keratin 10, which are found in cells called keratinocytes..., keratinocytes become fragile and are easily damaged, which can lead to blistering in response to friction or...
Genetics Home Reference: Dowling-Degos disease by nih.gov , particularly cells that make up the skin, hair, and nails. Keratin 5 is produced in cells called keratinocytes... intermediate filaments. These filaments assemble into strong networks that help attach keratinocytes...
Genetics Home Reference: benign chronic pemphigus by nih.gov to be particularly important for the normal function of cells called keratinocytes, which are found in the outer layer of the skin... storage affects keratinocytes more than other types of cells. The abnormal regulation of calcium impairs...
Paget's disease if Nipple- Review by Dr.Prashant Jani Patient Expert from surrounding keratinocytes. Although this phenomenon has been described as acantholysis, Paget disease cells do not have intercellular connections with keratinocytes; they instead are tucked individually or...
Paget's disease if Nipple- Review by Dr.Prashant Jani Patient Expert from surrounding keratinocytes. Although this phenomenon has been described as acantholysis, Paget disease cells do not have intercellular connections with keratinocytes; they instead are tucked individually or...

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