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Dengue Tetravalent Vaccine Containing a Common 30 Nucleotide Deletion in the 3'-UTR of Dengue Types 1, 2, 3, and 4 by nih.gov Description of Invention: The invention relates to a dengue virus tetravalent vaccine... of dengue virus serotypes 1, 2, 3, and 4. The previously identified delta30 attenuating mutation, created...
Development of Mutations Useful for Attenuating Dengue Viruses and Chimeric Dengue Viruses by nih.gov and economic loss, there is a shortage of effective vaccines. This invention relates to dengue virus mutations that may contribute to the development of improved dengue vaccines. Site directed and random mutagenesis techniques...
How Dengue Virus Infects Cells by nih.gov Researchers have discovered a key step in how the dengue virus infects a cell... by mosquitoes. Dengue fever usually starts with a fever, joint pain, rash...
Monoclonal Antibodies That Bind or Neutralize Dengue Virus by nih.gov where Aedes albopictus and Aedes aegypti mosquitoes are abundant. Dengue infection produces fever, rash... Description of Invention: Among the arthropod-borne flaviviruses, the four dengue virus...
Scientists Discover How Dengue Virus Infects Cells by MedNews Patient Expert into the cell’s interior. Researchers have discovered a key step in how the dengue virus infects a cell..., symptoms may become more severe. Patients with the severe form of the disease, dengue hemorrhagic fever...
Multiplex Assay for Detection of Dengue Virus by nih.gov fever, dengue hemorrhagic fever, and dengue shock syndrome). CDC researchers have developed a RT-PCR... an improved method for rapid and accurate serotyping of dengue virus in clinical and research settings...
Development of Dengue Virus Type 3 Vaccine Candidates by nih.gov hundred (100) million cases of dengue fever, making development of an effective vaccine a priority... Description of Invention: The disease burden associated with dengue virus infection...
Generation of Wild-Type Dengue Viruses for Use in Rhesus Monkey Infection Studies by nih.gov million cases of dengue fever and 500,000 cases of the more severe form of dengue virus infection known as dengue hemorrhagic fever/dengue shock syndrome (DHFIDSS). This latter disease is seen predominately...
Development of Antigenic Chimeric St. Louis Encephalitis Virus/Dengue Virus Type Four Recombinant Viruses (SLEV/DEN4) as Vaccine by nih.gov therapy is not available. The inventors have previously developed a WNV/Dengue4Delta30 antigenic... (prM and E) proteins on a dengue virus type 4 (DEN4) genetic background with a thirty nucleotide...

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