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It's well known that much of the medical research is done on men, as it is theorized that women have too many hormonal fluctuations over the course of their lives to give accurate information as to how well a particular dru 
into the tissues ?
The entire vascular tree could form a few 100 kilometer length.(Capillary /arterioles... tone for the large , small arteries and the arterioles and veins .This tone is vital for pushing...
diameter that determine the glomerular blood flow. As in any vascular bed, it is the arterioles that determine the resistance and hence the flow . These arterioles form the critical resistance points...
arterioles ?
It is somewhat similar to coronary events . ( With one major exception, coronary vesels... with more vigour to damage the cerebral arterioles. The reason systolic pressure is more important lies...
to smaller and smaller arterioles, and then to a complex network of tiny capillaries... the cycle again, thousands of times each day. The arterioles, venules and capillaries collectively form... 
into the veins and so then the sickle cells clog up the tiny capillaries, venuoles and arterioles in the body... capillary clogs up---now imagine that, in every single joint, capillary, arteriole and venuole in your body...
is pumped to all tissues in the body. In addition, arterioles, which are blood vessels that constrict and dilate to allow blood through are also affected. When high amounts of sodium are present, the arterioles...
the blocking off of tiny cappillaries, arterioles and venuoles (a sickle cell trait), which causes portions... 
I had seen several examples, I was starting to be able to distinguish between, say, arteries and arterioles, or veins...
across the arterioles to reach the venules .The venous circulation has the lowest pressure, it ends up at right atrium... 
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