Good hygiene, including thorough hand washing, will reduce the spread of roundworms.

In parts of the world where roundworms are commonly found, it is particularly important to take care when preparing food. Surfaces and hands should be clean and hygienic and food should be thoroughly cooked. Avoiding salads and raw fruit and vegetables is advised.

After treatment, it is important to prevent reinfection by washing your hands carefully. This is particularly important before and after food preparation, and when using the toilet. Keeping nails short and clean and disinfecting the toilet regularly will also help.