Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Vitamin E May Offer Benefits for Alzheimer’s

Posted Jun 11 2014 4:00pm

Vitamin E Vitamin E supplements are already known for offering multiple health benefits but a recent study may add another one to the list. The results of a study published in the Journal of the American Medical Association (JAMA) shows that supplementation of vitamin E slows decline in patients with mild Alzheimer’s.

The study was a large, rigorous, multicenter randomized placebo-controlled trial with 33 authors, carried out at 14 Veterans Affairs (VA) medical centers. It enrolled 613 patients age 53 to 96 with a diagnosis of possible or probable AD of mild to moderate severity who were already taking an acetylcholinesterase inhibitor (AChEI). 65% were on Donepezil, 32% on Galantamine, and 3% on Rivastigmine.

The results showed that participants got worse over the period of the study. However, individuals in the vitamin E group had a significantly slower decline than those in the placebo group (3.15 units less on the ADCS-ADL Inventory, annual rate of decline 19% less, and delay in progression of 6.2 months). The group taking both vitamin E and memantine did significantly worse than the group taking vitamin E alone. Adherence was estimated at 65-68%, which isn’t all that bad considering the age of patients and the effects of Alzheimer’s. They concluded that 2,000 IU of vitamin E significantly delayed clinical progression in activities of daily living in patients with mild to moderate AD who were also taking AChEI.

The results of this study bring some hope for Alzheimer’s patients but no one should start taking Vitamin E without the supervision of a physician. The Alzheimer’s Association’s call for caution as the high doses used in the ADCS study can negatively interact with other medications, including those prescribed to keep blood from clotting or to lower cholesterol.

Post a comment
Write a comment:

Related Searches