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Vitamin D and Brain Power

Posted Jun 18 2009 1:51pm

June 2, 2009 — Lower 25-hydroxyvitamin D [25(OH)D] levels in older men are associated with slower psychomotor processing speed, according to the results of a population-based, cross-sectional study reported in the May 21 Online First issue of the Journal of Neurology, Neurosurgery & Psychiatry.

“Although there is evidence that vitamin D inadequacy may be linked to adverse cognitive outcomes, results from studies on this topic have been inconsistent,” write David M. Lee, from the University of Manchester in Manchester, United Kingdom, and colleagues. “The aim of our trial was to examine the association between…25(OH)D levels and cognitive performance in middle-aged and older European men.”

At 8 centers taking part in the European Male Ageing Study, 3369 men, ranging in age from 40 to 79 years, underwent evaluation of cognitive performance and measurement of serum 25(OH)D levels by radioimmunoassay. Psychological testing included the Rey-Osterrieth Complex Figure (ROCF) test, the Camden Topographical Recognition Memory (CTRM) test, and the Digit Symbol Substitution Test (DSST). Physical activity, functional performance, and mood/depression were also evaluated. Locally weighted and linear regression models were used to explore associations between cognitive function and 25(OH)D levels.. more here…

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