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Vincent Racaniello

At virology blog, my goal is to educate you about viruses - the kind that make you sick. Why am I qualified to teach you virology? I have been studying viruses for over 30 years, starting in 1975, when I entered the Ph.D. program in Biomedical Sciences at Mt. Sinai School of Medicine of the City... Full Bio
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Ten years of virology blog by Vincent Racaniello Posted in: Blog Posts in General Medicine Photo by  Chris Suspect Ten years ago this month I wrote the first post at virology blog, entitled Are viruses living? Thanks to  EE Giorgi  for pointing out the t ... Read on »
Unexpected viral DNA in RNA virus-infected cells by Vincent Racaniello Posted in: Blog Posts in General Medicine Many years ago a claim was made that cells infected with respiratory syncytial virus contained infectious DNA copies of the viral genome. When this paper was published, r ... Read on »
A dancing matrix of viruses by Vincent Racaniello Posted in: Blog Posts in General Medicine Back in 1974, before it was possible to determine the sequence of a viral genome, before we knew much about the origin of viruses and their ability to move genes from org ... Read on »
TWiV 287: A potentially pandemic podcast by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #287 of the science show This Week in Virology, Matt Frieman updates the TWiV team on MERS-coronavirus, and joins in a discussion of whether we should further ... Read on »
What price antiviral drugs? by Vincent Racaniello Posted in: Blog Posts in General Medicine The Federal Drug Administration of the US approves new drugs solely on the basis of safety and effectiveness, with no value assessment. Pharmaceutical companies may set t ... Read on »
TWiV 286: Boston TWiV party by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #286 of the science show This Week in Virology, Vincent and Alan meet up with Julie and Paul at the General Meeting of the American Society for Microbiology in ... Read on »
A WORD on the constraints of influenza virus evolution by Vincent Racaniello Posted in: Blog Posts in General Medicine Evolutionary biologist John Maynard Smith used an analogy with a word game to explain how epistasis constrains the evolution of a protein. In this game, single letter ch ... Read on »
The next emerging threat by Vincent Racaniello Posted in: Blog Posts in General Medicine Ian Lipkin, Columbia University, New York, and Lyle Petersen, Centers for Disease Control and Prevention, Fort Collins, Colorado, discuss recently emerged pathogens, and ... Read on »
Therapeutic teamwork: Coupling oncolytic viruses with immunotherapy to destroy tumor cells by Vincent Racaniello Posted in: Blog Posts in General Medicine This article was written for extra credit by a student in my recently concluded  virology course . by Nayan Lamba A recent study by scientists at the Ludwig Cen ... Read on »
TWiV 285: Hokies go viral by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #285 of the science show This Week in Virology, Vincent meets up with XJ Meng and Sarah McDonald at Virginia Tech to talk about their work on viruses of swine ... Read on »
TWiV 284: By the pricking of my thumbs, something wicked this way comes by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #284 of the science show This Week in Virology, the TWiV team discusses how skin scarification promotes a nonspecific immune response, and whether remaining st ... Read on »
Should variola virus, the agent of smallpox, be destroyed? by Vincent Racaniello Posted in: Blog Posts in General Medicine Later this month (May 2014) the World Health Assembly will decide whether to destroy the remaining stocks of variola virus – the agent of smallpox – or to allow continu ... Read on »
Virology question of the week: What matters more, multiplicity of infection or virus concentration? by Vincent Racaniello Posted in: Blog Posts in General Medicine This week’s question comes from a graduate student studying virology, who writes: My professor recently said that really, the MOI doesn’t matter in a culture, it is ... Read on »
TWiV 283: No Reston for the weary by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #283 of the science show This Week in Virology, Jens Kuhn speaks with the TWiV team about filoviruses, including the recent Ebola virus outbreak in Guinea. ... Read on »
Unusual mortality pattern of 1918 influenza A virus by Vincent Racaniello Posted in: Blog Posts in General Medicine The 1918 influenza pandemic was particularly lethal, not only for the very young and the very old (as observed for typical influenza), but unexpectedly also for young a ... Read on »
TWiV 282: Tamiflu and tenure too by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #282 of the science show This Week in Virology, the TWiV team reviews a meta-analysis of clinical trial reports on using Tamiflu for influenza, and suggestions ... Read on »
Virology question of the week: why a segmented viral genome? by Vincent Racaniello Posted in: Blog Posts in General Medicine This week’s virology question comes from Eric, who writes: I’m working on an MPH and in one of my classes we are currently studying the influenza virus. I’d forgott ... Read on »
TWiV 281: The Salk legacy with Peter L. Salk by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #281 of the science show This Week in Virology, Vincent meets up with Peter L. Salk to talk about development of the first poliovaccine, eradication of poliomy ... Read on »
TWiV 280: Post viral by Vincent Racaniello Posted in: Blog Posts in General Medicine On episode #280 of the science show This Week in Virology, the TWiVmeisters answer listener email about the NEIDL, negative results, patenting MERS-coronavirus, human pap ... Read on »
Unraveling the NEIDL by Vincent Racaniello Posted in: Blog Posts in General Medicine The NEIDL (National Emerging Infectious Diseases Laboratory) at Boston University is a newly constructed biosafety level 4 facility which can be used to study the most da ... Read on »