Trades
- Freddy Garcia to the Phillies for Gavin Floyd and PTBNL
- Mets trade Brian Bannister to the Royals for AmbriorixBurgos
- Braves trade Horacio Ramirez to the Mariners for Rafael Soriano
- Cubs trade Freddie Bynum to the Orioles for Kevin Hart

Signings
- Jose Guillen to the Mariners
- Pedro Feliz to Giants
- Rich Aurilia to Giants
- J.D. Drew to Boston
- DewonBrazelton and Wayne Franklin to Kansas City
- Bengie Molina to Giants
- Mike Lieberthal to Dodgers
- Alan Embree to Oakland
- Dave Dellucci and Joe Borowski to the Indians
- Matt Stairs to the Blue Jays
- Jason Schmidt to Dodgers
- Ted Lilly to Cubs
- Daryle Ward to Cubs
- Gil Meche to Royals