Unfortunately, upon ingredient analysis, at least 30% of the product is silicones, and that is a low estimate. Silicones have long been used in skin care formulations as both emollients and to reduce the appearance of fine lines and wrinkles, but their effects are mostly temporary and cosmetic. For instance, according to the textbook Principles of Polymer Science and Technology in Cosmetics and Personal Care , silsesquioxane crosspolymers provide a water-resistant barrier, whereas dimethicone provides an improved feel/softness, and dimethicone copolyols reduce irritation with the skin. Besides their hydrating effects, there is really no proven long-term benefit to the use of silicones.
Besides antioxidants, the two other major anti-aging ingredients in this serum are retinyl palmitate and peptides (as acetyl hexapeptide-8 and palmitoyl oligopeptide).
Retinyl palmitate is a combination of pure retinol and palmitic acid (a substance typically used in cosmetics as a cleansing agent). When present in sufficiently high concentrations, retinyl palmitate displays results similar to that of retinol. And considering that retinol is one of the gold standards in the arsenal against aging in today’s market, I would say the inclusion of retinoids in this product is an excellent thing!
In the lower concentration of the two peptides is palmitoyl oligopeptide (AKA palmitoyl pentapeptide-4 or palmitoyl pentapeptide-3 or Matrixyl), a synthetic signaling peptide proven to increase the firmness of your skin following regular topical application by stimulating the production of collagen types I, III, and IV; fibronectin, elastin, and glycosaminoglycan within your skin. Palmitoyl oligopeptide was also shown by a 2005 study in the International Journal of Cosmetic Science to reduce the appearance of fine lines better than placebo when used over the course of 12 weeks. However, it is notable that the concentration of palmitoyl oligopeptide used in the study was 3 ppm; it is highly doubtful that Clinique Repairwear Laser Focus Wrinkle & UV Damage Repair Serum contains a similar concentration.