“No matter how blonde your hair or trim your figure, time eventually has its way.”
This is more like cigarettes and sun exposure, the two worst things you can do to your skin. The story posits that too much cosmetic surgery may be involved here. In this case, the cigarettes and the sun are more than half the problem. I’d wager she has had good plastic surgeons involved in her care, but they cannot defeat the signs of aging nearly as well when the cancer sticks and the sun are still in play.