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An Exciting New Product: Skinceuticals Phloretin CF

Posted Jun 16 2008 6:13pm

If you read my blog enough, you know that I am a diehardSkinceuticals CE Ferulicjunkie. I would probably inject, inhale, and snort the $128 serum if it were possible to do so. (And yes, this is me being sarcastic, haha.) :-)

So imagine my surprise when I discovered thatSkinceuticalshas a new serum:Skinceuticals Phloretin CF($128.00,Skinmedix.com). It’s kind-of likeCE Ferulicwas a Harvard grad, only to have its baby cousin Phloretin CF emerge and become a Rhodes Scholar:Phloretin CFis just that amazing.  Preliminary research demonstrates that it is basically a super antioxidant that not only fights free radicals, but also protects against DNA damage andpenetrates well into the skin.  As said in June 2008 issue ofOprah,“Phloretin, a natural extract that’s been studied as an anticancer agent, is the newest antioxidant available topically; research has shown it can penetrate the skin and provide significant UV protection.”  According toDr. Brenton B. Koch, M.D., F.A.C.S., SkinCeuticals developedPhloretin CFafter five extensive years of research. Dr. Kochelaborates in hisblog, “This powerhouse formulation divides and conquers when it comes to damage at every level. Phloretin CFprotects against not only free radicals, but the range of other reactive molecules known to cause damage and DNA mutations among integral cell types.  In addition, it corrects existing damage by stimulating the synthesis of essential proteins and fibers and accelerating cell turnover.”  Additional research inThe Journal of Biological Chemistryshows that phloretin is an inhibitor of sugar transport amongst red blood cells, which holds some level of promise as to the role phloretin may play in AGE formation and the subsequent hardening of the skin’s collagen.

So how doesPhloretin CFdiffer fromCE Ferulic?  Basically, Skinceuticals:

  • removed all the vitamin E (1% to 0%) and 5% of the vitamin C from CE Ferulic (from 15% to 10%)
  • kept the same level of ferulic acid as an antioxidant stabilizer (0.5%)
  • added in 2% phloretin (from 0% to 2%)

What is exciting about this is that 2% phloretin reportedly is a very powerful antioxidant, not only fighting free radicals, but also protecting DNA from future damage and penetrating the skin in a way the ingredients inCE Ferulicwere not shown to in published research.  What isnotexciting is that the product not only contains less vitamin C thanCE Ferulic, but took out the vitamin E altogether, and vitamin C and vitamin E in combination have many well-established functions together, including prevention of the formation ofcarcinogenic nitrosaminesand enhancing the photoprotective effects of sunscreen,as vitamin C has been reported to enhance UVA protection, whereas vitamin E is more effective against UVB radiation.  Vitamin C and vitamin E are also two antioxidants that are able to “borrow” an electron to enhance one another.

So which is better?  The word is still out, until some brilliant scientist decides to do a comparison study of 15% L-ascorbic acid and 0.5% vitamin E versus 10% L-ascorbic acid and 2.0% phloretin.  I say, if you are a cautious person, stick to the provenCE Ferulicuntil more research inevitably surfaces.  (And my own personal experience from doing a switch toPhloretin CF, which will be available on the blog on June 17. :-)) On the other hand, if you are a trendy person who likes to be the first to try new things, then I would tryPhloretin CF, because it is likely that 2.0% phloretin is equally or even more effective than 0.5% vitamin E, though one cannot be sure of such a thought.

At any rate, I lovePhloretin CF!  Be sure to come back on June 17 (and hopefully before, haha) to get the full scoop on my personal experiences from the switch! :-)

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