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Viagra For Women Despite Inconclusive Studies. Jeet v94, n10
Doctors say a growing number of women are taking the anti-impotence pharmaceutical drug Viagra despite the lack of studies that prove it will amplify Libido feelings for female sexual drive, desires and responses.
"I've heard reports from all around the country of doctors prescribing it off-label to women," Dr. John Brand, director of the Kelsey Institute for Research in Sex Gender and Reproduction.
The Viagra pill, approved by the FDA for men, increases blood flow to the penis, which can help men attain external reproductive organ erections. Preliminary studies suggest it might promote libido feelings of sexual drive, desires or arousal responses in women.
Once the Viagra pills are approved for one use, doctors can legally prescribe it "off-label" for an unapproved use. However, FDA certifies it safe and effective only in treating conditions for which it has been tested.
Trials are under way in Europe, but Viagra pills hasn't been proven safe or effective for women yet, says the drug's maker, Pfizer Inc. There is also no proof that the anti-impotence pharmaceutical drug does not hinder fertility or cause birth defects.
But that has not stopped women from trying it.
For instance in Minneapolis, 16 women were prescribed Viagra by obstetrician/gynecologist Mario Peting of the Mark Nicol Clinic. Fourteen reported improved feelings of better sexual drives, desires and arousal responses. Six women in Chicago have taken the pill through a study at Loyola University medical Center. Three have reported better feelings of sexual drives, desires and arousal responses.
Source: Men's Sexual Health Center Forum
Here is the abstract of that study.
“Sildenafil Treatment of Women With Antidepressant-Associated Sexual Dysfunction: A Randomized Controlled Trial” by H. George Nurnberg, MD; Paula L. Hensley, MD; Julia R. Heiman, PhD; Harry A. Croft, MD; Charles Debattista, MD; Susan Paine, MPH, JAMA. 2008;300(4):395-404. Context Antidepressant-associated sexual dysfunction is a common adverse effect that frequently results in premature medication treatment discontinuation and for which no treatment has demonstrated efficacy in women. Objective To evaluate the efficacy of sildenafil for sexual dysfunction associated with selective and nonselective serotonin reuptake inhibitors (SRIs) in women. Design, Setting, and Participants An 8-week prospective, parallel-group, randomized, double-blind, placebo-controlled clinical trial conducted between September 1, 2003, and January 1, 2007, at 7 US research centers that included 98 previously sexually functioning, premenopausal women (mean [SD] age 37.1 [6] years) whose major depression was remitted by SRIs but who were also experiencing sexual dysfunction.Intervention Forty-nine patients were randomly assigned to take sildenafil or placebo at a flexible dose starting at 50 mg adjustable to 100 mg before sexual activity. Main Outcome Measures The primary outcome measure was the mean difference in change from baseline to study end (ie, lower ordinal score) on the Clinical Global Impression sexual function scale. Secondary measures included the Female Sexual Function Questionnaire, the Arizona Sexual Experience scale-female version, the University of New Mexico Sexual Function Inventory-female version, a sexual activity event log, and the Hamilton Depression Rating scale. Hormone levels were also assessed. Conclusion In this study population, sildenafil treatment of sexual dysfunction in women taking SRIs was associated with a reduction in adverse sexual effects. Al Link Sexy Spiritual Relationships
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Posted by RxBlogger
I heard a growing number of women are taking Viagra despite the lack of studies that prove it will amplify Libido feelings for female sexual drive, desires and responses.