I'm about to do another IVF ccyle and I'm hearing confusing things about these tow drugs. I know why they are different, but I thought you took one or the other during an IVF cycle, not both. Now I've heard that you will be started on the Methylprednisolone around day 6 from the start of stimulation, increase the dosage at retrieval, keep this level of dosage until the pregnacy test and then taper/wean off over/at week 12. However, I have now heard that at the pregnancy test, you switch over onto Prednisolone instead and take that until week 12 when you then wean and taper. Just wondering, if this is the case, then why switch to the 'lesser' drug (for want of a better word) and do you still have to wean off of methylprednisolone? or can you just jump straight from one to the other? Help, confused!?