Can't wait 2 read through this thread! SO grateful 4 all of u who shared. More voices=more awareness re: #postpartum depression. #abcdrbchat
250 days ago
More news on SSRIs...a 2009 study presents information that taking antidepressants during pregnancy may increase odds of preeclampsia in the 3rd trimester. However, more research needs to be done because of the evidence already uncovered that anxiety and depression also increase preeclampsia odds.
A recent studysought to examine whether selective serotonin reuptake inhibitor (SSRI) antidepressants increase the risk of preeclampsia since serotonin may play a role in the etiology of preeclampsia through its vascular and hemostatic effects. Toh and colleagues analyzed data from 5,731 women with non-malformed infants and no history of hypertension who had participated in the Slone Epidemiology Center Birth Defects Study from 1998-2007. Risk of gestational hypertension and preeclampsia were compared between women who did and did not receive SSRIs during pregnancy....
While the present study suggests that SSRI treatmentamong pregnant women may be associated with a higher risk for gestationalhypertension and, particularly, preeclampsia, the authors addressed potential confounders for their findings, including depression itself. Several previous studies have shown a link between depression and anxiety and risk for preeclampsia, and it has been suggested that both conditions may trigger the pathogenic vascular processes that lead to gestational hypertension (by inducing vasoconstriction and uterine artery resistance).One Finnish studyquoted a threefold risk for preeclampsia among women with depression and anxiety.
A recent studysought to examine whether selective serotonin reuptake inhibitor (SSRI) antidepressants increase the risk of preeclampsia since serotonin may play a role in the etiology of preeclampsia through its vascular and hemostatic effects. Toh and colleagues analyzed data from 5,731 women with non-malformed infants and no history of hypertension who had participated in the Slone Epidemiology Center Birth Defects Study from 1998-2007. Risk of gestational hypertension and preeclampsia were compared between women who did and did not receive SSRIs during pregnancy....
While the present study suggests that SSRI treatmentamong pregnant women may be associated with a higher risk for gestationalhypertension and, particularly, preeclampsia, the authors addressed potential confounders for their findings, including depression itself. Several previous studies have shown a link between depression and anxiety and risk for preeclampsia, and it has been suggested that both conditions may trigger the pathogenic vascular processes that lead to gestational hypertension (by inducing vasoconstriction and uterine artery resistance).One Finnish studyquoted a threefold risk for preeclampsia among women with depression and anxiety.
Here's a link to the MGH blog that posted the study results...