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The beginning effects of Parkinson's Disease (PD) include resting tremor (slight shakiness in the hand while the hand is at rest) and rigidity (muscle stiffness).  Typically these symptoms are unilateral (one-sided) to start.  As PD progresses they soon develop on both sides.

A few other early signs of PD are Bradykinesia (slow movements), balance problems, fatigue that lasts over two weeks, gastrointestinal problems (such as constipation), slurred speech and a change in personality.