Obesity researcher, Professor Philippe Froguel and his team have discovered a new obesity gene.
Apparently, this gene (PCSK1) plays a part in the maturation of various hormones that control food intake.
This means that if you have a mutated version of this gene, you are predisposed to severe obesity. Severe obesity, not just regular, run of the mill obesity.
The Details
PCSK1 produces an enzyme called proconvertase 1.
Proconvertase 1 activates several hormones and circulating peptides that are involved in controlling appetite –insulin,glucagon,GLP1, and pro-opiomelanocortin (POMC).
The conclusion of this study is that even apparently minor abnormalities in a proconvertase 1 are enough to significantly increase the risk of severe obesity and to lead to excessive weight in the general population.
So what does this mean?
This means that if your PCSK1 gene is mutated, you are probably obese. Just like if your were born with acongenital leptin deficiency.
So, what percentage of the population is walking around with a deformed PCSK1 gene.
We don’t know, and neither do the scientists.
What causes this gene mutation?
We don’t know, and neither do the scientists.
Can this mutation be corrected?
We don’t know, and neither do the scientists.
Should obese individuals rely on science to provide them with a treatment for a potentially rare genetic mutation that most likely did not cause their obesity in the first place?
NO.
oops, sorry, my objectiveness slipped a little..
We don’t know, and neither do the scientists.
The study is published in the journal,Nature Genetics.
.
If you like what you see here,click here for updatesorShare this Postwith the rest of the world.
Thanks in Advance.
Obesity researcher, Professor Philippe Froguel and his team have discovered a new obesity gene.
Apparently, this gene (PCSK1) plays a part in the maturation of various hormones that control food intake.
This means that if you have a mutated version of this gene, you are predisposed to severe obesity. Severe obesity, not just regular, run of the mill obesity.
The Details
PCSK1 produces an enzyme called proconvertase 1.
Proconvertase 1 activates several hormones and circulating peptides that are involved in controlling appetite –insulin,glucagon,GLP1, and pro-opiomelanocortin (POMC).
The conclusion of this study is that even apparently minor abnormalities in a proconvertase 1 are enough to significantly increase the risk of severe obesity and to lead to excessive weight in the general population.
So what does this mean?
This means that if your PCSK1 gene is mutated, you are probably obese. Just like if your were born with acongenital leptin deficiency.
So, what percentage of the population is walking around with a deformed PCSK1 gene.
We don’t know, and neither do the scientists.
What causes this gene mutation?
We don’t know, and neither do the scientists.
Can this mutation be corrected?
We don’t know, and neither do the scientists.
Should obese individuals rely on science to provide them with a treatment for a potentially rare genetic mutation that most likely did not cause their obesity in the first place?
NO.
oops, sorry, my objectiveness slipped a little..
We don’t know, and neither do the scientists.
The study is published in the journal,Nature Genetics.
.
If you like what you see here,click here for updatesorShare this Postwith the rest of the world.
Thanks in Advance.