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The Web site of the National Institutes of Health (http://www.nih.gov)   NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and... Full Bio
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A Molecular Link Between Sleep and Liver Fat by nih.gov Posted in: Blog Posts in General Medicine Scientists have discovered a molecular link between the body's biological clock and fat production in the liver. The finding may help explain why disrupting daily cycles, ... Read on »
A Mouse Model for Human Osteoarthritis by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Osteoarthritis (OA) is the most common form of arthritis and affects more than 20 million Americans, costing billions of dollar ... Read on »
A Mouse Model for Systemic Inflammation in Glucocerebrosidase-Deficient Mice with Minimal... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Gaucher disease, the most common lysosomal storage disease, is an inherited metabolic disorder in which harmful quantities of t ... Read on »
A Mouse Model for Type 2 Diabetes by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Diabetes affects over 120 million people worldwide (16 million in the US) and is a major health problem with associated health ... Read on »
A Mouse Model of von Hippel-Lindau Disease by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: The current invention embodies a mouse model which has been rendered a conditional homozygous knockout at the murine chromosome ... Read on »
A Mouse with a Targeted Mutation in the Uncoupling Protein-3 (upc3) Gene by nih.gov Posted in: Blog Posts in Health Education Description of Invention: The NIH announces the development of a transgenic mouse with a targeted mutation in the ucp3 gene. The ucp3 gene is implicated ... Read on »
A Neuronal Avalanche Size (NAS) Assay to Screen for Cognitive Enhancers and Anti-Epileptics by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Currently available methods of detecting and measuring EEG activity only crudely classify normal and abnormal activity or disti ... Read on »
A New ?Destination? for Protein Expression: A Lentiviral Gateway? Destination Vector for... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: A laboratory at the Science Applications International Corporation in Frederick, MD (SAIC-Frederick) has developed a lentiviral ... Read on »
A New Class of Antibiotics: Natural Inhibitors of Bacterial Cytoskeletal Protein FtsZ to Fight... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: The risk of infectious diseases epidemic has been alarming in recent decades. This is not only because of the increase incident ... Read on »
A New Class of Broad-spectrum Antibiotics: Naturally-occurring Chrysophaetins and Their Analogues by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: This invention, offered for licensing and commercial development, relates to a new class of naturally occurring antimicrobial c ... Read on »
A New Class, Now in Session: the First HLA Class II Restricted T Cell Receptor that Recognizes the... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: NIH scientists have developed T cell receptors (TCRs) against the melanoma antigen family A3 (MAGE-A3) tumor antigen in the con ... Read on »
A New Pot1 Variant Gene as a Diagnostic Biomarker for Hereditary Non-polyposis Colorectal Cancer by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: The diagnosis of Hereditary Nonpolyposis Colorectal Cancer (HNPCC) is difficult because the disease lacks phenotypic signs that ... Read on »
A New Technology for Identification of Genes Expressed in Hypoxia Conditions by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Low concentrations of oxygen (hypoxia) are a major pathophysiological condition conducive for angiogenesis, necessary for tumor ... Read on »
A New Transmission Blocking Vaccine for Leishmania Infection by nih.gov Posted in: Blog Posts in Drug Addiction Description of Invention: A novel transmission blocking vaccine has been developed that can eliminate or reduce the number of Leishmania chagasi parasite ... Read on »
A Newly Discovered Bacterium in the Family Acetobacteraceae by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Available for licensing and commercial development is a newly discovered bacterium in the Acetobacteraceae family. This bacter ... Read on »
A Non-invasive Post-treatment Strategy for Stroke by Intranasal Delivery of Cocaine- and... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: Cocaine and amphetamine-regulated transcript (CART) is a neuropeptide known to protect against ischemic brain injury when admin ... Read on »
A Novel and Efficient Technology for Targeted Delivery of siRNA by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: The biological phenomenon of RNA interference (RNAi) has much promise for developing therapeutics to a variety of diseases. Ho ... Read on »
A Novel Chimeric Bifunctional Protein for Prevention and Treatment of HIV Infection by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: This invention relates to bifunctional fusion proteins effective in HIV neutralization. Specifically, the invention is a geneti ... Read on »
A Novel DNA Vaccine for the Treatment of Malignancies Expressing Immature Laminin Receptor Protein by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: This invention describes a new potent chemoattractant-based DNA vaccine to evoke therapeutic anti-tumor responses against tumor ... Read on »
A Novel Growth Factor and Anti-Apoptotic Agent for Promoting Lung Development and Treating Lung... by nih.gov Posted in: Blog Posts in General Medicine Description of Invention: This invention discloses the novel use of the uteroglobin-related protein 1 (UGRP1), also known as secretoglobin family 3A memb ... Read on »