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Neurodoc .. Patient Expert

San Francisco, California
I am a practicing neurologist in Florida who blogs items I have read or studied recently for my own later use.  The public is free to read the blog  if it benefits them.  I post sporadically to six blogs, covering general neurology, dementia, behavioral neurology, stroke, multiple... Full Bio
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Alz biomarkers in normal pressure hydrocephalus by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Graff-Radford NR.  Alzheimer CSF biomarkers may be misleading in normal-pressure hydrocephalus.  Neurology 2014; 83:1573-1575. Preshunt in NPH have low Ab42 and t ... Read on »
posterior cortical atrophy review paper by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia http://ac.els-cdn.com/S1474442211702897/1-s2.0-S1474442211702897-main.pdf?_tid=63b29014-f231-11e3-9c1c-00000aab0f26&acdnat=1402578149_2d87bf974149da4f3ae868083858a9fd ... Read on »
ADAS cog flawed by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia PLYMOUTH, United Kingdom -- December 19, 2012 -- New research suggests that the cognitive test used in Alzheimer's disease (AD) drug trials is flawed. The cur ... Read on »
raloxifene and cognition by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia OBJECTIVE:: The aim of this study was to examine the effects of raloxifene compared with those of placebo on verbal memory, mental processing speed, depr ... Read on »
AFIB and cognitive decline without stroke by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies; Marzona I, O'Donnell M, ... Read on »
mitazepine for weight loss in AD by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Weight loss is a frequent complication of Alzheimer disease (AD), associated with increased morbidity and mortality. Increased appetite and weight gain are k ... Read on »
donepezil for LBD by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Donepezil for dementia with Lewy bodies: A randomized, placebo-controlled trial; Mori E, Ikeda M, Kosaka K, on behalf of the Donepezil-DLB Study Investigators; Annal ... Read on »
Higher vitamin D level protective against AD? by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Higher Vitamin D Dietary Intake Is Associated With Lower Risk of Alzheimer's Disease: A 7-Year Follow-up; Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Herrm ... Read on »
Memantin plus vitamin D in Alzheimer's disease by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Effectiveness of the combination of memantine plus vitamin d on cognition in patients with Alzheimer disease: a pre-post pilot study; Annweiler C, Herrmann FR, Fan ... Read on »
High dose rivastigmine in Alz disease by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Aim: Determine whether patients with Alzheimer's disease demonstrating functional and cognitive decline, following 24-48 weeks of open-label treatm ... Read on »
CSF profiles and variant dementia by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Neurology 2012; 78:47 -54 CSF profiles of tau and abeta are extremely effective differentiating some dementias but not others. Markers were t(total) tau, p (phosphoryla ... Read on »
Vitamin D and risk of cognitive decline in elderly persons by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A, Ferrucci L, Melzer D; Archives of Internal Medicine 170 (13), 1135-41 (Jul 2010) BAC ... Read on »
Treating Neuropsychiatric Symptoms in Dementia With Lewy Bodies: A Randomized Co by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Culo S, Mulsant BH, Rosen J, Mazumdar S, Blakesley RE, Houck PR, Pollock BG; Alzheimer Disease & Associated Disorders (Jul 2010) Sensitivity to psychotropic me ... Read on »
donepezil and apathy by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease; Waldemar G, Gauthier S, Jones R, Wilkinson D, Cummings J, Lopez O, Zhang R, Xu Y, Sun Y, ... Read on »
Cholinesterase inhibitor minutiae by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia 1.  oral donepezil is not affected by food, unlike rivastigmine and galanthamine 2.  donepezil has 3-5 hours to peak onnset v. 0.5-1 for galanthamine and rivastigmine (oral ... Read on »
GOVERNMENT REPORT ON RISK FACTORS FOR ALZ DISEASE by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia http://www.ahrq.gov/downloads/pub/evidence/pdf/alzheimers/alzcog.pdf   UPSHOT GOOD:  PHYSICAL ACTIVITY, COGNITIVE ENGAGEMENT BAD; SMOKING, E4 ALLELE, DI ... Read on »
Frontotemporal dementia- clinical pearls by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia 1.  Frontotemporal dementia is a clinical term, frontolobar degeneration is a pathologic term 2.  Preservation of memory, ability to keep track of day events, timing of s ... Read on »
Dementia classifications-- rapid FTD's, by abnormal protein by Neurodoc .. Patient Expert Posted in: Blog Posts in Alzheimer's & Dementia Frontotemporal dementia subtypes and genetics-- rapidly progressive subtypes 1. FTD and parkinsonism due to mutation on chromosome 17 on gene encoding microtubul ... Read on »