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Two Genes identified by Mayo Clinic as potential therapeutic targets for Multiple Sclerosis

Posted Nov 17 2009 10:20pm
Mayo Clinic identifies 2 genes as potential therapeutic targets for multiple sclerosis
Published Release 11-Sept-2009

Early research holds promise for new therapies and better prediction of patient outcomes

ROCHESTER, Minn. -- A Mayo Clinic study has found that two genes in mice were associated with good central nervous system repair in multiple sclerosis (MS). These findings give researchers new hope for developing more effective therapies for patients with MS and for predicting MS patients' outcomes. This study will be presented at the Congress of the European Committee for Treatment and Research in Multiple Sclerosis in Dusseldorf, Germany, on Sept. 11, 2009.

"Most MS genetic studies have looked at disease susceptibility -- or why some people get MS and others do not," says Allan Bieber, Ph.D., a Mayo Clinic neuroscientist and author of this study. "This study asked, among those who have MS, why do some do well with the disease while others do poorly, and what might be the genetic determinants of this difference in outcome."

Mayo Clinic provides care for nearly 2,500 patients with MS each year.

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