The Ottawa Hospital, General Campus, 4th Floor, Multiple Sclerosis Research Unit, 501 Smyth Rd, Box 606, Ottawa, ON, Canada K1H8L6.
BACKGROUND: Multiple Sclerosis (MS) patients lacking CSF oligoclonal bands are purported to have a milder course of disease. We reviewed the natural history of oligoclonal band (OCB) - negative (OCB-) compared to OCB positive (OCB+) patients.
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