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Stem Cell Breakthrough: Mass-Production Of 'Embryonic' Stem Cells

Posted Jan 14 2009 8:22pm
Information obtained from the Accelerated Cure Project


Stem Cell Breakthrough: Mass-Production Of 'Embryonic' Stem Cells From A Human Hair Published


The first reports [268] of the successful reprogramming of adult human cells back into so-called induced pluripotent stem (iPS) cells, which by all appearances looked and acted like embryonic stem cells, created a media stir. But the process was woefully inefficient: Only one out of 10,000 cells could be persuaded to turn back the clock.

Now, a team of researchers led by Juan Carlos Izpisúa Belmonte at the Salk Institute for Biological Studies, succeeded in boosting the reprogramming efficiency more than 100-fold, while cutting the time it takes in half. In fact, they repeatedly generated iPS cells from the tiny number of keratinocytes attached to a single hair plucked from a human scalp. "Having a very efficient and practical way of generating patient-specific stem cells, which unlike human embryonic stem cells, wouldn't be rejected by the patient's immune system after transplantation brings us a step closer to the clinical application of stem cell therapy," says Belmonte, PhD., a professor in the Gene Expression Laboratory and director of the Center of Regenerative Medicine in Barcelona, Spain.

[268] http://www.eurekalert.org/pub_releases/2008-10/si-srs101708.php

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