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Society-funded Researchers Find Pattern of Gene Activity Associated with High Risk for MS

Posted Jan 14 2009 8:24pm
Source: Nat'l MS Society
Published: Aug 13, 2008

Society-funded Researchers Find Pattern of Gene Activity Associated with High Risk for MS

In a major step toward discovering molecules that may be used as “markers” to predict MS disease activity and progression, researchers identified a pattern of gene expression (i.e., patterns of genes being turned on or off) within immune cells that was associated with quick conversion to MS in a study of 37 people with CIS (clinically isolated syndrome, a first event suggestive of MS). Senior author Sergio Baranzini, PhD, Jean-Cristophe Corvol, PhD and colleagues (University of California, San Francisco) report the results in an early online publication from Proceedings of the National Academy of Sciences of the USA (August 5, 2008). This study was funded by several sources including a Collaborative MS Research Center Award to Jorge Oksenberg, PhD, from the National MS Society.

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