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National MS Society’s Promise: 2010 Campaign Identifies Key Signals in Myelin Repair

Posted Nov 17 2009 10:20pm

Jul 13, 2009

Team Funded by National MS Society’s Promise: 2010 Campaign Identifies Key Signals in Myelin Repair

A team funded in part by the National MS Society’s Promise: 2010 Campaign has demonstrated that the “Wnt signaling pathway” – a complex network of proteins that interact during brain development – may also play an important role in the failure of nerve-protecting myelin to repair itself in people with MS. Stephen P. J. Fancy, PhD, David Rowitch, MD, PhD (University of California, San Francisco) and colleagues – including Robin J. M. Franklin, PhD, DVM (University of Cambridge) report their findings in Genes and Development (2009 Jul 1;23(13):1571-85).

Drs. Rowitch and Franklin are members of the international Promise: 2010 Nervous System Repair & Protection team led by Professor Charles ffrench-Constant (University of Edinburgh and University of Cambridge, UK), who, along with three other collaborating teams, are laying the groundwork for clinical trials aimed at protecting and restoring function in people with MS.

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