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Multiple Sclerosis: IMPAX Reports Positive Results in Phase III Trial

Posted Jan 14 2009 8:24pm
Centre Daily Times 4:42 AM PDT

Thursday, Aug. 07, 2008
IMPAX Reports Positive Results in Phase III Trial with IPX056
-Provides Update on Brand Pharmaceutical Program- -Company Presenting Today at the Bank of America Specialty Pharmaceutical Conference-


HAYWARD, Calif. — IMPAX Laboratories, Inc. today announced that IPX056, an investigational extended-release formulation of baclofen, has met its clinical endpoints in a Phase III study of spasticity in multiple sclerosis patients. The Company also is providing an update on its brand pharmaceutical product program, which resides in its IMPAX Pharmaceuticals Division.

In a 173-patient, placebo and active comparator-controlled double blind Phase III study with a seven-week open label follow on, IPX056 was shown to be effective versus placebo in reducing spasticity in multiple sclerosis patients. IPX056 is an extended-release formulation of baclofen, the drug of choice in the treatment of spasticity, which has the potential to offer improved control of symptoms and dosing convenience.

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