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COPAXONE(R) May Have Ability to Protect Against Axonal Injury Over the Long-Term in Relapsing-Remitting Multiple Sclerosis

Posted Jul 31 2009 10:38am
Additional Long-Term Efficacy in Both Clinical and MRI Parameters Also Highlighted at European Neurological Society Meeting


KANSAS CITY, MO -- (MARKET WIRE) -- 06/30/05 -- New data presented at the European Neurological Society Meeting (ENS) demonstrated key clinical and magnetic resonance imaging (MRI) effects of COPAXONE® (glatiramer acetate injection) in the treatment of relapsing-remitting multiple sclerosis (RRMS). Results highlighted sustained beneficial effects on cerebral axonal injury and the value of starting COPAXONE® treatment early to slow the accumulation of long-term disability as measured by the Expanded Disability Status Scale (EDSS).

MRS results suggest beneficial effect of COPAXONE® on cerebral axonal injury

Brain n-acetylaspartate (NAA) levels, a marker of neuronal integrity and function, are measured by magnetic resonance spectroscopy (MRS). An increase in brain NAA levels relative to creatinine (NAA/Cr ratios) indicates a recovery of injured nerve cells or neurons in the brain. Preventing or minimizing damage to nerve cells is critical in reducing long-term disability in multiple sclerosis.


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