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Cognitive dysfunction in primary progressive multiple sclerosis: a neuropsychological and MRI study

Posted Nov 17 2009 10:20pm

summary: There are very few studies of cognitive dysfunction in people with primary progressive MS (PPMS). In this study the authors compared a group of people with primary progressive MS with a group of secondary progressive MS and a group of healthy volunteers. They found that (SPMS) people with MS scored lower than controls on some tests, such as those related to attention and information processing, verbal fluency and memory. However, people with PPMS and with SPMS performed tests similarly. Moreover, the authors found that people with a higher number of lesions performed worse than people with a lower lesion burden.

authors: Ukkonen M, Vahvelainen T, Hämäläinen P, Dastidar P, Elovaara I

source: Mult Scler. 2009 Jun 25

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