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Topiramate (Topamax) for Headache & Migraine Prevention Can Increase Occurrence of Kidney Stones

Posted Sep 07 2008 8:08pm

Topiramate (Topamax) is a neuronal stabilizing agent (aka anticonvulsant medication) that is FDA-approved for and prescribed for headache and Migraine prevention.

Researchers at the University of Texas Southwestern Medical Center at Dallas (UT Southwestern) have have completed a study showing that topiramate can increase the propensity for calcium phosphate kidney stones. Although there has been anecdotal evidence of this potential side effect and much discussion of it, this is the first study to formally investigate the issue and examine the mechanism of stone formation.Read our feature article.

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