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Pituitary Hormone May Be Linked to Osteoporosis

Posted Oct 01 2008 8:19pm
A hormone produced by the pituitary gland may play a role in bone loss in postmenopausal women, challenging the notion that declining estrogen levels are solely responsible for the problem.

High levels of the hormone, pituitary-derived follicle-stimulating hormone (FSH), caused an increase in bone loss in mice. And mice who lacked either the FSH hormone or its receptor became resistant to bone loss, even if they showed evidence of estrogen deficiency.

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