The substance found in wild yam cream is a precursor to progesterone - unfortunately not usable by the human body as is. (That's why the wild yam cream doesn't seem to work.) Pro-Gest is derived from barbasca yam/or soybean and converted to progesterone in the lab. The starting material is diosgenin and then made into various hormones – progesterone being identical to body progesterone. Only USP (United States Pharmacopeia) progesterone is natural progesterone. Two examples are Pro-Gest and Natural Woman progesterone cream. I hope this helps - let me know how it goes or if you have any other questions.
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