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Hormone Replacement Therapy Associated with Decreased Survival in Women with Lung Cancer

Posted Oct 01 2008 8:20pm

According to a recent article published in the Journal of Clinical Oncology, women with lung cancer who have taken hormone replacement therapy (HRT) may have a significantly poorer overall survival than those who have never taken HRT.

Hormone replacement therapy (HRT) is often prescribed for women during menopause. During menopause, a natural phase of the female lifecycle, the ovaries produce significantly less estrogen, ovulation ceases, and menstruation ends. For many women, menopause has uncomfortable side effects; these may include hot flashes, sleep disturbances, depression, mood swings, and anxiety. Additionally, menopause may also be accompanied by increased urinary tract infections, incontinence, vaginal discomfort due to a lack of estrogen-based lubrication, and decreased bone density.

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