There is no hard and fast rule. As a woman's eggs age, there is a greater chance of birth defects, but many healthy "Change of Life" babies as we used to call them have been born. If you are pregnant and concerned, check with your doctor about amniocentesis, ultrasound, genetic testing etc to rule out some (not all) potential problems.

Good luck.  Let us know how it goes.

Lynette Sheppard RN  Health Maven   Menopause Goddess Blog