Clindamycin is typically prescribed for aerobic gram positive cocci and/or anaerobic gram negative rods as well as some protozoal infections. Typically we think of skin & soft tissue infections.
The nose is known to harbor and be colonized with Staphylococcus aureus. Colonization is different from infection although bacteria are present in both. In the former, there is no local or systemic evidence of infection, eg redness, swelling, pain, fever, etc. So one can be colonized but w/o infection while an infection can never occur w/o colonization.
I suspect that your physician concerned that your nasal sore is due to Staph aureus, and is even more concerned about Methicillin resistant staphylococcus aureus or MRSA, which is a major cause of infection both inside & outside the hospital. The big problem with MRSA is the difficulty associated with treating this bacteria since it has developed resistance to many antibiotics. So it's considered better to nip in the bud. But in reality, the best way to keep from spreading it is to wash hands.
It's doubtful that anyone can ever get rid of MRSA. Perhaps just temporarily w/antibiotics such as Clindamycin while one has an open wound. But chances are pretty good that the MRSA will return after your wound has healed & you've finished yoru antibiotics. Therefore, the best way to prevent spreading MRSA is to always wash your hands before handling anything.
By the way, since Clindamycin is associated with a pretty miserable diarrhea called C diff, ask your physician if s/he performed a nasal culture to confirm the presence of MRSA. After all, you'd hate to take an antibiotic if you didn't need to do so.
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