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C1q Nephropathy: What You Need to Know by Matt S. Posted in: Blog Posts in Kidney Failure I saw a 20 year old African American male in clinic with nephrotic range proteinuria, reduced GFR and no signs or symptoms of a systemic disease. His mother developed ... Read on »
Immortality by Matt S. Posted in: Blog Posts in Kidney Failure A few months ago, a paper was published in the International Journal of Epidemiology that caused a sensation in it's home country - Denmark. Using registry data, and t ... Read on »
Unusual transplant immunology case by Matt S. Posted in: Blog Posts in Kidney Failure File this under something that we are never likely to see in clinical practice. In 2002 a fascinating case report was published in the New England Journal of Medicine ... Read on »
Hyponatremia Guidelines - NephJC by Matt S. Posted in: Blog Posts in Kidney Failure Tomorrow night will be the 4th edition of the Nephrology Journal Club on twitter.The article this week is unusual - it is a clinical practice guideline for the managem ... Read on »
Deceased Donor Kidney Allocation 2014 by Matt S. Posted in: Blog Posts in Kidney Failure In the USA in June 2013 the OPTN/UNOS Board of Directors approved amendments to the OPTN policy for deceased donor kidney allocation. These ideas have be ... Read on »
Bedside Urinalysis - Blood by Matt S. Posted in: Blog Posts in Kidney Failure All to often now doctors in well-resourced hospitals rely on high tech, expensive and sometimes invasive tests to make a diagnosis. One of the most basic ... Read on »
SGLT-2 and the genesis of hyperfiltration by Matt S. Posted in: Blog Posts in Kidney Failure Over at eAJKD , Swapnil Hiremath has a nice post about the potential for SGLT-2 inhibitors to prevent diabetic nephropathy based on a review article published on the top ... Read on »
The use of IVIg in Kidney Disease by Matt S. Posted in: Blog Posts in Kidney Failure It’s time for a quick nephro-centric summary of immune globulin use. Immune globulin, usually administered intravenously (IVIg), is made from pooled human plasma and used ... Read on »
Endothelin Antagonism for Diabetic Nephropathy: Nephrology Twitter Journal Club by Matt S. Posted in: Blog Posts in Kidney Failure The next Nephrology Twitter Journal Club (@NephJC) will discuss a study in JASN describing the use of Atrasentan, a selective Endothelin-A receptor blocker, in dia ... Read on »
Nephrology Twitter Journal Club (#NephJC): CKD Screening & Education by Matt S. Posted in: Blog Posts in Kidney Failure The articles for Nephrology Twitter Journal Club will be chosen by you, the users. Please post links to potential articles using the #NephJC hashtag. The ... Read on »
The ongoing debate about the definition of CKD in the elderly by Matt S. Posted in: Blog Posts in Kidney Failure In NDT this month, there is a nice series of articles outlining the ongoing debate about whether or not an eGFR<60 should be considered a disease, particularly in the ... Read on »
Hepatitis C cure on the Horizon: Implications for Nephrology by Matt S. Posted in: Blog Posts in Kidney Failure You have probably noticed the flurry of articles published this week in the NEJM , coinciding with the International Liver Congress meeting in London, reporting incredibl ... Read on »
The use of Rituximab in Kidney Disease by Matt S. Posted in: Blog Posts in Kidney Failure Rituximab, the monoclonal chimeric anti-CD20 antibody, is an effective B-Cell depleting agent and continues to gather data for its use in a wide range of conditions relevan ... Read on »
Perils of Estimating GFR in Patients with Cirrhosis by Matt S. Posted in: Blog Posts in Kidney Failure In my attempt to highlight nephrology content in non-renal journals, I will this month focus on a series of articles in Hepatology concerning eGFR in cirrhotic patient ... Read on »
NephMadness 2014 Part 8 - Biologics Bracket by Matt S. Posted in: Blog Posts in Kidney Failure Places are still open for the 10th running of this one week course, held annually at the Mount Desert ... Read on »
NephMadness 2014 Part 6 - Kidney Stone Bracket by Matt S. Posted in: Blog Posts in Kidney Failure The electrolyte bracket contains a mixture of the old staples of nephrology mixed with some new kids on the block trying to muscle in on established territory, Vaptan ... Read on »
NephMadness 2014 Part 5 - Renal Replacement Bracket by Matt S. Posted in: Blog Posts in Kidney Failure As ESRD prevalence continues to increase, the kidney transplant list continues to grow meaning longer waiting times for deceased donor transplantation. Living donation ... Read on »
NephMadness 2014 Part 3 - Kidney Regeneration Bracket by Matt S. Posted in: Blog Posts in Kidney Failure In the AKI bracket one team caught my eye, RIPC, Remote Ischemic Preconditioning. This is a procedure of inducing transient ischemia ... Read on »
NephMadness 2014 Part 1- Hypertension Bracket by Matt S. Posted in: Blog Posts in Kidney Failure In the poisons and toxins bracket I learnt some interesting facts. The Dietary Supplement Health and Education Act of 1994 (DSHEA 94) is an example of t ... Read on »
The use of Eculizumab in transplantation: What’s new? by Matt S. Posted in: Blog Posts in Kidney Failure Eculizumab is a humanized monoclonal antibody (mAb) that binds the complement protein C5 blocking its cleavage into C5a and C5b, thereby preventing the formation of t ... Read on »