Matt S.'s Posts - Wellsphere

Heavy Metal by Matt S. Posted in: Blog Posts in Kidney Failure The excellent drug development blog " In the pipeline " highlighted a fascinating phase 2 trial that is ongoing at the moment. Pentoxifylline is a methylxanthine phsop ... Read on »

Does she drink tea? by Matt S. Posted in: Blog Posts in Kidney Failure I was quickly moving along through my busy university clinic, seeing another CKD patient when the nurse came to inform me that the patient’s hemoglobin was criti ... Read on »

Hemoglobin Targets in CKD by Matt S. Posted in: Blog Posts in Kidney Failure For anyone who would like to read a thorough review of the current evidence with regard to Hb targets and the use of ESAs in patients with CKD and those on dialysis, I ... Read on »

Page Kidney by Matt S. Posted in: Blog Posts in Kidney Failure Patient with a history of kidney transplant s/p biopsy 2 weeks prior now undergoing chemotherapy treatment for leukemia develops acute abdominal pain, worsening renal funct ... Read on »

Which thiazide? - the debate continues by Matt S. Posted in: Blog Posts in Kidney Failure The debate about which thiazide diuretic to prescribe patients with hypertension has been going on for years without resolution and both HCTZ and chlorthalidone have the ... Read on »

New potential drug targets in ADPKD by Matt S. Posted in: Blog Posts in Kidney Failure Currently there is no good treatment for the most common inherited cause of ESRD, adult polycystic kidney disease. There have been a number of high profile trial ... Read on »

Is it time to wake up to online Hemodiafiltration? by Matt S. Posted in: Blog Posts in Kidney Failure There has been a lot of interest recently in online Hemodiafiltration (olHDF) with multiple studies published in the past year. It is a technique which ha ... Read on »

Bad Odor by Matt S. Posted in: Blog Posts in Kidney Failure Cystinosis is an autosomal recessive disease caused by a mutation in CTNS, which encodes the lysosomal transporter of cystine. This leads to intracellular cysti ... Read on »

Image of the Month - Pathology by Matt S. Posted in: Blog Posts in Kidney Failure A woman in her early 30s presented to the renal clinic with sudden onset edema. Her urinalysis revealed 4+ protein and 3+ blood. Dysmorphic red cells were noted on micro ... Read on »

Origins of Renal Physiology by Matt S. Posted in: Blog Posts in Kidney Failure Every year we like to publicize the MDIBL origins of renal physiology course. This is a great opportunity for renal fellows and the fact that it is free apart from tr ... Read on »

Skin Lesions in Dialysis - Part 5 by Matt S. Posted in: Blog Posts in Kidney Failure Nail changes in renal failure: Half and half nails (Lindsay's nails) can be found in patients with any degree of azotemia. The prevalence is about 21% in dialysis p ... Read on »

Skin Lesions in Dialysis - Part 4 by Matt S. Posted in: Blog Posts in Kidney Failure Acquired Perforating Dermatoses: Perforating dermatoses are a group of conditions characterized by transepidermal elimination of dermal material (collagen, ela ... Read on »

Skin Lesions in Dialysis - Part 3 by Matt S. Posted in: Blog Posts in Kidney Failure Nephrogenic Systemic Fibrosis (NSF) No post or summary on skin disorders in renal failure can omit NSF. This has been mentioned in multiple previous posts on RFN - a ... Read on »

Electrolyte Disorders involving Tubular Channels by Matt S. Posted in: Blog Posts in Kidney Failure Though adult nephrologists infrequently encounter these disorders in clinic, the Board Exam loves them. Below a short table describing some of these gain- and loss-of-funct ... Read on »

Bardoxolone - The Final Chapter - Part 2 by Matt S. Posted in: Blog Posts in Kidney Failure One of the issues surrounding the study of bardoxolone in animal models was that, because of the way that it is metabolized in rats and mice, it is highly toxic when giv ... Read on »

New JAMA Reader by Matt S. Posted in: Blog Posts in Kidney Failure JAMA has a new platform called the JAMA Network Reader that you can use to get access to content from any of the JAMA journals (includes what were formerly called Archives ... Read on »

Skin Lesions in Dialysis - Part 2 by Matt S. Posted in: Blog Posts in Kidney Failure Phototoxic skin disorders in renal failure: Patients with renal failure or ESRD secondary SLE can have a photosensitive skin rash. For example: Discoid ... Read on »

Concept Map of Hypokalemia by Matt S. Posted in: Blog Posts in Kidney Failure Read on »

MDRD vs CKD-EPI in Transplantation by Matt S. Posted in: Blog Posts in Kidney Failure With the results of the eAJKD brackets posted by Gearoid, I thought this article might be pertinent to stimulate further the debate... This article just came out on Transpl ... Read on »

Skin Lesions in Dialysis Patients - Part 1 by Matt S. Posted in: Blog Posts in Kidney Failure These are my brackets for the eAJKD nephmadness. My winner is a number 10 seed coming out of left field. For me, the importance of the MDRD trial is th ... Read on »

Matt S.

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