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Mark Pool, MD

I practice general surgical pathology and serve as laboratory medical director at Riverside Medical Center in Kankakee, Illinois. I am also an adjunct attending at Rush Medical College in Chicago. My specialty challenges and humbles me because of the sublime variation and complexity of diseases... Full Bio
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FDA draft guidelines on IVD "companion diagnostics" by Mark Pool, MD Posted in: Blog Posts in Cancer Digital Pathology Insights blog posted a nice succinct comment on the FDA draft guidance on companion diagnostics that are of acute interest for anyone interested in ... Read on »
WCLC 2011 Oral Presentations: Tumor microenvironment by Mark Pool, MD Posted in: Blog Posts in Cancer So I'm finally finished sorting through the abstracts from the 14th World Conference on Lung Cancer that I recently attended and this begins a series of posts of what I ... Read on »
ALK -Positive Lung Adenocarcinoma: NEJM Case Records by Mark Pool, MD Posted in: Blog Posts in Cancer The July 14, 2011 issue of The New England Journal of Medicine features a nice case report as part of the weekly "Case Records of the MGH" series.  I thought those inte ... Read on »
DigiPath, Inc. announces partnership with PathXL by Mark Pool, MD Posted in: Blog Posts in Cancer Press release from new company in digital pathology universe, DigiPath, Inc., who announced their launch last week whilst I was on vacation.  Interesting partnership.   ... Read on »
AABB SmartBrief: Mismatched cord blood transplants can be effective by Mark Pool, MD Posted in: Blog Posts in Cancer Studies: Mismatched cord blood, marrow transplants can be effective Results of transplants with unrelated umbilical cord blood or mismatched bone marrow were comparab ... Read on »
Deep Vein Thrombosis Awareness by Mark Pool, MD Posted in: Blog Posts in Cancer Here's another radio spot I did earlier this year for the CAP's "Hometown Radio Interview" on increasing awareness of deep vein thrombosis (DVT). ... Read on »
Colorectal Cancer Awareness by Mark Pool, MD Posted in: Blog Posts in Cancer Here's another radio spot I recently did for the CAP's "Hometown Radio Interview" program regarding colorectal cancer screening awareness. Read on »
Tweeting for 14th World Conference on Lung Cancer by Mark Pool, MD Posted in: Blog Posts in Cancer I will be in attendance on Tuesday, July 5 at the 14th World Conference on Lung Cancer in Amsterdam and tweeting over the course of the day.  Please join me on Twitter. ... Read on »
STD Awareness by Mark Pool, MD Posted in: Blog Posts in Cancer Here's a brief radio spot I recently did for the CAP regarding awareness of sexually-transmitted disease (STD) awareness. Read on »
Incidentalomas revisited by Mark Pool, MD Posted in: Blog Posts in Cancer Dr. Bruce Friedman posted a thoughtful blog on Lab Soft News recently concerning "incidentalomas" (" How to Avoid the Risks of a CT Incidentaloma ").  This post happene ... Read on »
Systems biology for studying cancer by Mark Pool, MD Posted in: Blog Posts in Cancer This month's issue of Future Oncology has a well-written editorial from Dr. John McDonald from Georgia Tech regarding systems biology in cancer research.  This is a fre ... Read on »
DDR2 Kinase Mutations in Lung Squamous Cell Carcinoma by Mark Pool, MD Posted in: Blog Posts in Cancer Yes--you read that right! The journal Cancer Discovery reports in a publish ahead-of-print article (abstract) the discovery of mutations in the discoidin domain rec ... Read on »
ASCO issues Provisional Clinical Opinion on EGFR testing in Non-Small-Cell Lung Cancer by Mark Pool, MD Posted in: Blog Posts in Cancer Hot off the electronic press is the PCO issued by ASCO recommending that patients with advanced stage NSCLC should have their tumors tested for EGFR mutation if they ar ... Read on »
Notes and impressions from CAP Futurescape '11 by Mark Pool, MD Posted in: Blog Posts in Cancer First, a disclaimer.  I was only able to attend CAP Futurescape on Saturday, April 16.  Although this was the majority of the conference, the Sunday morning session had ... Read on »
ASCO/CAP clarifications to ER/PR/HER2 testing guidelines by Mark Pool, MD Posted in: Blog Posts in Cancer ASCO is publishing a clinical notice regarding clarifications to previously published guidelines for HER2 testing and estrogen receptor (ER) and progesterone receptor ( ... Read on »
Hallmarks of cancer v. 2.0 by Mark Pool, MD Posted in: Blog Posts in Cancer In 2000, Douglas Hanahan and Robert Weinberg initially proposed six hallmarks of cancer that form an organizing principle for understanding the remarkable diversity of ... Read on »
What is the CAP's NewsPat ... by Mark Pool, MD Posted in: Blog Posts in Cancer What is the CAP's NewsPath? It is a series of articles and podcasts on current topics in laboratory medicine written by pathologists for the medical community. I even h ... Read on »
Aberrant Wnt1 and beta-catenin expression in NSCLC by Mark Pool, MD Posted in: Blog Posts in Cancer This month's April 2011 Journal of Thoracic Oncology has an interesting paper by Xu and colleagues ( abstract ) that examines Wnt1 expression in non-small cell lung can ... Read on »
Evidence for tissue-specific differences in EMT by Mark Pool, MD Posted in: Blog Posts in Cancer Remodeling of the extracellular matrix is a key process in cancer invasion.  Matrix metalloproteases (MMPs) have been shown to be important in ECM remodeling but identi ... Read on »
Henry VIII, the Kell blood group system and the McLeod syndrome by Mark Pool, MD Posted in: Blog Posts in Cancer ScienceDaily (Mar. 3, 2011) — Blood group incompatibility between Henry VIII and his wives could have driven the Tudor king's reproductive woes, and a genetic cond ... Read on »