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Mark Pool, MD

I practice general surgical pathology and serve as laboratory medical director at Riverside Medical Center in Kankakee, Illinois. I am also an adjunct attending at Rush Medical College in Chicago. My specialty challenges and humbles me because of the sublime variation and complexity of diseases... Full Bio
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Update in TB and Non-TB Mycobacterial Disease by Mark Pool, MD Posted in: Blog Posts in Cancer Dick Menzies and Payam Nahid "Update in Tuberculosis and Nontuberculous Mycobacterial Disease 2012", American Journal of Respiratory and Critical Care Medicine, Vol. 188, No ... Read on »
RBC immunization in sickle cell disease--revisited by Mark Pool, MD Posted in: Blog Posts in Cancer Stella Chou and co-authors published a very interesting and somewhat disquieting paper in the August 8, 2013 edition of Blood (abstract), "High prevalence of RBC immunizatio ... Read on »
Does anemia impact hospital readmission rates after CABG surgery? by Mark Pool, MD Posted in: Blog Posts in Cancer Nadine Shehata and colleagues studied this question in a recently published article (abstract) in the August 2013 issue of Transfusion. This is a single-institution study of ... Read on »
AHA White Paper on Utilization of Medical Resources by Mark Pool, MD Posted in: Blog Posts in Cancer The AHA has published a free white paper, "Appropriate Use of Medical Resources," that can be accessed and downloaded as a pdf file from the link. Of interest to pathologist ... Read on »
New government regs threaten medical testing labs - The Hill's Congress Blog by Mark Pool, MD Posted in: Blog Posts in Cancer Interesting (and frustrating) post from The Hill. Why are hospital and small independent labs being punished because of the actions of large commercial labs abusing the Medi ... Read on »
Role of Bone Marrow-Derived HPCs in Pulmonary Fibrosis by Mark Pool, MD Posted in: Blog Posts in Cancer Interesting article from AJRCCM just published online that adds to accumulating data implicating circulating bone marrow-derived hematopoietic progenitor cells in the develo ... Read on »
ETS2 mediates tumor suppressor function and MET inhibition in lung adenocarcinoma by Mark Pool, MD Posted in: Blog Posts in Cancer There was a very intriguing paper published online by Clinical Cancer Research on May 9 last week that should be of interest for those involved in lung cancer research. The ... Read on »
NKX2-1/TTF-1 drives pulmonary-specific differentiation in lung adenocarcinoma by Mark Pool, MD Posted in: Blog Posts in Cancer Snyder et al. recently published an intriguing report in Molecular Cell (21 March 2013) (featured free article) in which they convincingly demonstrate how tumors in which Nk ... Read on »
CAP releases guidelines for validating whole slide imaging by Mark Pool, MD Posted in: Blog Posts in Cancer The College of American Pathologists has released guidelines for validating whole slide imaging. While stating the lack of FDA approval for using WSI for primary diagnosis, ... Read on »
BRAF mutations in colorectal cancer: mini-review by Mark Pool, MD Posted in: Blog Posts in Cancer There has been a recent flurry of papers and reports from ASCO-GI 2013 pushing more molecular testing in colorectal cancer (CRC) and its clinical significance with regard to ... Read on »
Atomic force microscopy! EMT and idiopathic pulmonary fibrosis by Mark Pool, MD Posted in: Blog Posts in Cancer Here is a very intesting article I recently found with some very cool technology: Abstract: Epithelial-mesenchymal transition (EMT) is closely implicated in the pathogenesis ... Read on »
Imaging tumors in the future by Mark Pool, MD Posted in: Blog Posts in Cancer Baohong Yuan and Joshua Rychak have written an interesting review in the February 2013 American Journal of Pathology that outlines emerging techniques based on ultrasound to ... Read on »
Pathologists to Blame for Hindering Acquisition of Cancer Tissue for Genomic Testing? by Mark Pool, MD Posted in: Blog Posts in Cancer Medscape recently posted an article that discusses the need for standards for acquiring, preserving and storing cancer tissue, citing a recent Viewpoint article in JAMA by D ... Read on »
New Device to Check Margins in Breast Cancer Surgery by Mark Pool, MD Posted in: Blog Posts in Cancer Just a follow-up to yesterday's post regarding surgical margins in breast cancer. Will this device obviate inking the specimen or the debate about how much margin is "enough ... Read on »
Controversy: Surgical Margins in Breast Cancer by Mark Pool, MD Posted in: Blog Posts in Cancer What is a clear margin in breast-conserving cancer surgery? ASCO Connection (link) hosts a point-counterpoint discussion by two contributors regarding surgical margins in br ... Read on »
Video: Dr. Jack West discusses changing views on molecular testing in NSCLC by Mark Pool, MD Posted in: Blog Posts in Cancer The Lungevity blog features a video of Dr. Jack West from Swedish Cancer Institute in Seattle discussing his evolving views regarding molecular testing for actionable driver ... Read on »
Epithelial-Mesenchymal Transition and Lung Cancer: Mechanism for Resistance to EGFR-TKIs? by Mark Pool, MD Posted in: Blog Posts in Cancer Despite all of the encouraging clinical results with molecularly targeted therapies against non-small cell lung cancer, there are still important and significant questions t ... Read on »
General Surgical Pathologist is Dead by Mark Pool, MD Posted in: Blog Posts in Cancer Excellent post from Digital Pathology Blog on the demise of the general surgical pathologist! It's amazing (and worrisome) that this happened so quickly in our field. What h ... Read on »
CAP Public Comment Period for New Biomarker Reporting Checklists by Mark Pool, MD Posted in: Blog Posts in Cancer Take a look at the new cancer biomarker reporting checklists proposed by the College of American Pathologists for breast, colon and lung cancers. You don't have to be a CAP ... Read on »
Multilocular Cystic Renal Cell Carcinoma by Mark Pool, MD Posted in: Blog Posts in Cancer Multilocular cystic renal cell carcinoma is an uncommon but diagnostically challenging variant of renal cell carcinoma that fortunately has an excellent prognosis. Histologi ... Read on »