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Mark Pool, MD

I practice general surgical pathology and serve as laboratory medical director at Riverside Medical Center in Kankakee, Illinois. I am also an adjunct attending at Rush Medical College in Chicago. My specialty challenges and humbles me because of the sublime variation and complexity of diseases... Full Bio
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Digital case challenge by Mark Pool, MD Posted in: Blog Posts in Cancer Sigmoid colon polyp identified in screening colonoscopy in a 56 year old woman.  My diagnosis and comment tomorrow.   Read on »
Digital case challenge 1.0 by Mark Pool, MD Posted in: Blog Posts in Cancer Thanks to Ole Eichhorn from Aperio, who generously scanned slides from a couple recent interesting cases of mine, I offer a digital slide as a "challenge case." ... Read on »
Digital Case Challenge: Adenocarcinoma with Non-mucinous Bronchioloalveolar Features by Mark Pool, MD Posted in: Blog Posts in Cancer It has been a long while since I've posted one of the cases I've worked on and now its time to clear off my desk (before our CAP inspection). The patient is an 83-y ... Read on »
Digital Case Challenge: Enterobius vermicularis (Pinworm) by Mark Pool, MD Posted in: Blog Posts in Cancer The day before the (U.S.) Thanksgiving, I saw this case.  It was identified as simply "colon biopsy" but the pathology assistant noted white thready "mucosal" fragments ... Read on »
Digital case challenge: Incidental sigmoid colon polyp by Mark Pool, MD Posted in: Blog Posts in Cancer An IHC stain for S-100 protein is shown below.  IHCs for actin, desmin, CD34, and AE1/AE3 cytokeratins were negative.   Rare ganglion-like cells were iden ... Read on »
Digital case challenge: Laryngeal lesion mimicking carcinoma by Mark Pool, MD Posted in: Blog Posts in Cancer It's been quite awhile since I posted a challenging case, so here it goes. Clinical history: 43-year-old woman with recent onset of persistent hoarseness presents to ... Read on »
Digital Case Challenge: Pleuropulmonary amyloidosis by Mark Pool, MD Posted in: Blog Posts in Cancer A 68-year-old man presents with a history of recurrent bilateral pleural effusions over the past six months and recent CT scan of the chest showing persistent small bil ... Read on »
Digital Case Challenge: Pseudomelanosis duodeni by Mark Pool, MD Posted in: Blog Posts in Cancer I saw this biopsy yesterday and thought it was a curious little finding--pseudomelanosis duodeni is the lovely and impressive name given to this rare but appa ... Read on »
Digital Case Challenge: Rectal mucosal "schwannona" by Mark Pool, MD Posted in: Blog Posts in Cancer I'm finally emerging from a hiatus from blogging after the holidays and discoursing second-year medical students on lung pathology for the last 2 weeks.  So I'd like to ... Read on »
Digital Case: Simple mucocele of the appendix by Mark Pool, MD Posted in: Blog Posts in Cancer Finally, I'm working on sharing some interesting cases that have come across my desk recently! We've seen some interesting appendix pathology of late, including this case. H ... Read on »
Digital Pathology "Arms Race": Roche to buy BioImagene by Mark Pool, MD Posted in: Blog Posts in Cancer Roche announced on Monday that it is purchasing BioImagene ( WSJ article ).  The fact that the (former) BioImagene digital pathology system--and the intellectual property ... Read on »
Digital pathology article in "CAP Today" by Mark Pool, MD Posted in: Blog Posts in Cancer Dr. Keith Kaplan at Digital Pathology Blog pointed this one out as a good article discussing the recent FDA meeting regarding whole-slide imaging (WSI) technolo ... Read on »
Disruptive Integration and Health Care by Mark Pool, MD Posted in: Blog Posts in Cancer When Disruptive Integration Comes to Health Care Posted using Interesting article containing an interview with Dr. Jason Hwang co-author of The Innovator’s Pre ... Read on »
Does anemia impact hospital readmission rates after CABG surgery? by Mark Pool, MD Posted in: Blog Posts in Cancer Nadine Shehata and colleagues studied this question in a recently published article (abstract) in the August 2013 issue of Transfusion. This is a single-institution study of ... Read on »
Dose of platelets in prophylactic transfusions for severe thrombocytopenia by Mark Pool, MD Posted in: Blog Posts in Cancer Slichter and colleagues published a multi-institutional randomized trial in the February 18 issue of New England Journal of Medicine (article abstract) that evaluates t ... Read on »
Dr. Google, Consultant by Mark Pool, MD Posted in: Blog Posts in Cancer Dr. Emmanuel Macias, a generous reader of this blog and Canadian pathologist, recently related to me a case that he signed out that illustrates the use of the I ... Read on »
Dr. R2D2--Computerized pathologist? by Mark Pool, MD Posted in: Blog Posts in Cancer Meet C-Path, the iJobPlodd version of the 21st century pathologist. The December 3rd-9th, 2011issue of The Economist has an article in this "Technology Quarterly" section en ... Read on »
Early adopters of using social networking in health care by Mark Pool, MD Posted in: Blog Posts in Cancer I decided to tackle The Histories by Herodotus this summer, after having enjoyed reading Thucydides' The Peloponnesian War last summer, and came across a fascinating descrip ... Read on »
Easy read article on epigenomics by Mark Pool, MD Posted in: Blog Posts in Cancer Lay press article from the New York Times summarizing research on the epigenome.  Quick read if you have a few minutes. Read on »
EGAPP recommendations for gene expression testing in breast cancer by Mark Pool, MD Posted in: Blog Posts in Cancer Another paper from the EGAPP Working Group in Jan. 09 Genetics in Medicine of great interest concerns recommendations for gene expression profiling in breast ca ... Read on »