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How long to treat metastatic breast cancer. by Mark Levin Posted in: Blog Posts in Cancer It is common practice to continue treating metastatic breast cancer patients as long as responses are expected. NCCN recommends singel agents mostly but also a few comb ... Read on »
Refractory Acute Lymphocytic Leukemia: Role of Stem Cell Transplantation by Mark Levin Posted in: Blog Posts in Cancer Although acute lymphoblastic leukemia is curable in one third of adult patients, results vary greatly on account of different clinical, immunologic, and cytogenetic/gen ... Read on »
Prolonged Neupogen administration after a stem cell transplant by Mark Levin Posted in: Blog Posts in Cancer   There is some concern that administration of Neupogen will delay engraftment of non-myeloid cells after a stem cell transplant but a recent review found this not ... Read on »
Thalidomide and Leukine for prostate cancer by Mark Levin Posted in: Blog Posts in Cancer Both Leukine and thalidomide are investigational for prostate cancer, singly or together.  Much research had gone on about the effects of thalidomide and the relat ... Read on »
CAD for MRI by Mark Levin Posted in: Blog Posts in Cancer CAD assists radiologist in interpreting MRIs by color coding areas with differing accumulation of contrast. Its value has nto been proven. Computer-aided detection has ... Read on »
Erbitux for pancreatic cancer by Mark Levin Posted in: Blog Posts in Cancer Erbitux is an attractive drug to investigate for panceatic cancer. Unfortunately it has generally come up short in trials. The addition of the targeted agent Erbitux® (ce ... Read on »
Treatment of intravascular lymphoma by Mark Levin Posted in: Blog Posts in Cancer Inravascular lymphoma is a fairly new entity that is only recently described. It is is a rare form of diffuse LBCL characterized by preferential intravascular growth of ... Read on »
IV gammaglobulin for ITP before epidural anesthesisa. by Mark Levin Posted in: Blog Posts in Cancer The Cut-off platelet cound is not known. Older literature says: one hundred thousand. While IVIG has some role in presurgical situations, plt. ct of sixty eight is ... Read on »
Ova-1 test by Mark Levin Posted in: Blog Posts in Cancer OVA-1 is not securely established to be superior to Ca-125. Although there was a study determined that incorporating OVA1 in lieu of CA125 improved the sensitivity of t ... Read on »
Hypodiploid Acute lymphocytic leukemia by Mark Levin Posted in: Blog Posts in Cancer Children and adolescents with ALL and hypodiploidy with fewer than 44 chromosomes have a poor outcome despite contemporary therapy. Patients with hypodiploid leukemia c ... Read on »
Non-Hodgkin's lymphoma followup guidelines by Mark Levin Posted in: Blog Posts in Cancer Guideliens disagree how long to follow lymphomas but the literaure favors those who do NOT recommend routine imaging. NCCN (DLCL and follicular) recommends: •Repeat ... Read on »
Diagnosing inflammatory breast cancer(IBC). by Mark Levin Posted in: Blog Posts in Cancer Mammography, MRI or ultrasound often show suspicious signs; however in a significant proportion of cases they would miss a diagnosis.Clinical presentation is typical on ... Read on »
MRA for temporal arteritis by Mark Levin Posted in: Blog Posts in Cancer Temporal arteritis, or giant cell arteritis, is a common systemic vasculitis of unknown etiology. Ttemporal artery biopsy, a fairly easy procedure,  is standard for the ... Read on »
Hyperbaric oxygen for late radiation tissue toxicity by Mark Levin Posted in: Blog Posts in Cancer Radiation therapy can ahve proximal as well as delayed(late) radiation tissue injury(LRTI).  LRTI affecting the head, neck and lower end of the bowel can be improved wi ... Read on »
Partial Breast Irradiation by Mark Levin Posted in: Blog Posts in Cancer There are a number of guidelines that have considered the status of Partial Breast Irradiation, which  requires a clinician to insert 10 to 20 catheters through multipl ... Read on »
Neoadjuvant chemotherapy for ovarian cancer by Mark Levin Posted in: Blog Posts in Cancer The combination of paclitaxel and carboplatin in a three weeks schedule has emerged as the current standard approach for the adjuvant treatment of ovarian cancer. Afte ... Read on »
Hepatoblastoma by Mark Levin Posted in: Blog Posts in Cancer Hepatoblastoma is a rare pediatric cancer that can be cured by surgery. Preoperative chemotherapy followed by complete surgical excision according to International Soci ... Read on »
Surveillance for endometrial cancer by Mark Levin Posted in: Blog Posts in Cancer Current guidelines of the National Comprehensive Cancer Network (NCCN) and the American Congress of Obstetricians and Gynecologists recommend physical examination every ... Read on »
Pigmented Villonodular Synovitis and Gleevec by Mark Levin Posted in: Blog Posts in Cancer There are two types of Pigmented Villonodular Synovitis. Diffuse PVNS affects the entire synovium and typically occurs in large joints such as the knee or hip. Localize ... Read on »
Revlimid for prostate cancer. by Mark Levin Posted in: Blog Posts in Cancer Much research had gone on about the effects of thalidomide and the related drug Revlimid on prostate cancer. Thalidomide is listed by AHFS for prostate cancer. Revlimid ... Read on »