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Tarceva for esophageal cancer by Mark Levin Posted in: Blog Posts in Cancer Erlotinib has shown activity individually, as single drugs, or in combination with chemotherapy in upper gastro-intestinal cancers, including esophageal and gastro-esop ... Read on »
Oral appliances for snoring and Obstructive Apnea by Mark Levin Posted in: Blog Posts in Cancer Obstructive sleep apnea (OSA) is a prevalent disorder, which consists of recurring partial or complete occlusion of the upper airway during sleep, resulting in oxyhemog ... Read on »
Neulasta after treatment for AML by Mark Levin Posted in: Blog Posts in Cancer Patients with acute myeloid leukemia (AML) are often neutropenic becasue of leukemia and they also experience profound neutropenia following induction and/or consolidat ... Read on »
Predictive tests for shunting normal pressure hydrocephalus. by Mark Levin Posted in: Blog Posts in Cancer Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by gait disturbance, dementia, and/or urinary incontinence without causative disorders, and ... Read on »
Urine PCA3 by Mark Levin Posted in: Blog Posts in Cancer The widely used PSA blood marker is well established. However, the poor specificity of the PSA test for detecting cancer, or for differentiating indolent cancers from c ... Read on »
Neupogen: Dose by Mark Levin Posted in: Blog Posts in Cancer NCCN, ASCO and ASH guidelines recommend routine use of Neulasta® or Neupogen (filgrastim) for patients with an overall risk of FN of 20% or greater. Previous studies ha ... Read on »
Interim PET for Hodgkin's by Mark Levin Posted in: Blog Posts in Cancer Interim PET may provide important prognostic information and guide therapy. My reading of the evidence is that NCCN does recommend interim PET. NCCN for Hodgkin's does ... Read on »
PET for inital staging of Head and Neck cancer. by Mark Levin Posted in: Blog Posts in Cancer A recent guideline(Yoo et al) echoes this recommendation but goes beyond it. It says: "Positron emission tomography (PET) is recommended in the M and bilateral nodal st ... Read on »
Xeloda second line for colorectal cancer by Mark Levin Posted in: Blog Posts in Cancer XELODA (capecitabine) is indicated as first-line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is prefer ... Read on »
Tykerb with Herceptin by Mark Levin Posted in: Blog Posts in Cancer Lapatinib is an oral receptor tyrosine kinase inhibitor, inhibiting both the ErbB-1 and ErbB-2 receptors. Lapatinib has been shown to have activity in ErbB-2–overexpres ... Read on »
Temodar and Avastin for fibrous tumor/ hemangiopericytoma by Mark Levin Posted in: Blog Posts in Cancer Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to ... Read on »
First line Avastin for ovarian cancer by Mark Levin Posted in: Blog Posts in Cancer At the 2010 American Society of Clinical Oncology Annual conference in Chicago, the Gynecologic Oncology Group(GOG) presented the results of the latest clinical trial f ... Read on »
PET for Anaplastic Lymphoma by Mark Levin Posted in: Blog Posts in Cancer Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an act ... Read on »
Novo TTF device for Glioblastoma by Mark Levin Posted in: Blog Posts in Cancer Novo TTF was FDA approved in April 2011 under orphan disese designation for recurrent glioblastoma.. Several prominent neuronoologists were trained in tis use and it no ... Read on »
Anemia of chronic kidney disease by Mark Levin Posted in: Blog Posts in Cancer According to The National Kidney Foundation of The United States of America 1 CKD is defined as (1) evidence of kidney damage based on abnormal urinalysis results (e.g. ... Read on »
Goblet cell carcinoid by Mark Levin Posted in: Blog Posts in Cancer Goblet cell carcinoid (GCC) also known as crypt cell consists of a neuroendocrine component and a conventional carcinoma. Since it was identified in 1969 there has been ... Read on »
IVIG in Waldenstrom's by Mark Levin Posted in: Blog Posts in Cancer The hypogammaglobinemia and impaired T-cell function associated with Waldesntrom's macroglobulinemia predispose patients to potentially serious infections. CLL is a sim ... Read on »
Somatuline Depot (lanreotide acetate) for carciniod syndrome. by Mark Levin Posted in: Blog Posts in Cancer Somatuline Depot (lanreotide acetate) is an injectable, sustained-release formulation of lanreotide, an octapeptide somatostatin analog that inhibits Insulin-like growt ... Read on »
Tamiflu for prophylaxis by Mark Levin Posted in: Blog Posts in Cancer   Most guidelines for  prophylaxis of influenza in patients with cancer and on chemotherapy suffice with recommending vaccination. Some mention antiviral prophylaxi ... Read on »
Revlimid for myeloma maintenance by Mark Levin Posted in: Blog Posts in Cancer Lenalidomide is an immunomodulatory drug and a structural analogue of thalidomide which has been developed by Celgene. REVLIMID (lenalidomide) in combination with dexam ... Read on »