Mark Levin's Posts - Wellsphere

Tarceva for head and neck cancer by Mark Levin Posted in: Blog Posts in Cancer Tarceva is currently FDA approved for pancreatic cancer in combination with gemcitabine and for non-small cell lung cancer for second line. There are ongogn trials in head and ... Read on »

Revlimid for AML with 13q abnormality. by Mark Levin Posted in: Blog Posts in Cancer Revlimid is a derivative of thalidomide with less toxic side effects. A multicenter U.S. trial has reported hematologic activity of Revlimid in patients with myelodysplastic s ... Read on »

Temodar and Xeloda for neuroendocrine cacner by Mark Levin Posted in: Blog Posts in Cancer CVS/Caremark policy considers Temodar unapproved for lack of efficacy or of harm. Most of the available information is in abstract form. A retrospective review suggest that a ... Read on »

Role of 5FU is pancreatic cancer progressing after gemcitabine by Mark Levin Posted in: Blog Posts in Cancer 5 florouracyl is an older drug but it has some resposne in pancreatic cancer, as does its analogue, Xeloda. Unfortunately its role in combination patients who progressed after ... Read on »

Rebuilder Neuropathy Treatment System TENS for chemotherapy induced neuropathy by Mark Levin Posted in: Blog Posts in Cancer The Rebuilder Neuropathy Treatment System is primarily a TENS unit, except that it adds an EMS signal to passively exercise the calf muscles to stimulate the venous muscle pum ... Read on »

Xeloda combinations for thymoma by Mark Levin Posted in: Blog Posts in Cancer Thymoma is usually treated with surgery. Where surgery is inappropriate, chemotherapy concurrent with, or sequential to, radiation therapy is recommended. Cisplatin-based comb ... Read on »

ASHAP for salvage for Hodgkin's by Mark Levin Posted in: Blog Posts in Cancer Patients with Hodgkin's disease, which is either refractory or recurs after frontline chemotherapy with MOPP (mechlorethamine, vincristine, procarbazine, and prednisone), ABVD ... Read on »

Sprycel for glioblastoma by Mark Levin Posted in: Blog Posts in Cancer In one preclinical study, Dasatinib in combination with temozolomide more effectively increased the therapeutic efficacy of temozolomide than when dasatinib was combined with ... Read on »

Hypercoagulability testing in asymptomatic patients with a family history. by Mark Levin Posted in: Blog Posts in Cancer The test for Factor V Leiden was most often used in nonacute outpatient settings by primary care practitioners, in combination with other tests for procoagulant disorders. A r ... Read on »

Followup after resection of bladder cancer by Mark Levin Posted in: Blog Posts in Cancer There are not many studies of followup of a completely resected bladder cancer. However, a recent study fails to demonstrate a survival benefit for detecting tumor recurrence ... Read on »

Sprycel after failure of Gleevec in GIST. by Mark Levin Posted in: Blog Posts in Cancer Sprycel (dasatinib) is currently in trials for various types of sarcoma. Dasatinib, a small-molecule inhibitor of Src kinase activity, is a promising cancer therapeutic agent ... Read on »

Sculptra for HIV lipodystrophy by Mark Levin Posted in: Blog Posts in Cancer Sculptra® is approved by the FDA for restoration and/or correction of the signs of facial fat loss, or lipoatrophy, in people with human immunodeficiency virus. Sculptra&r ... Read on »

Temodar, Avastin and radiation for Glioblastoma by Mark Levin Posted in: Blog Posts in Cancer Glioblastoma is a disease with a very poor prognosis. Avastin in various combinations has been studied for a number of years in this disease and Avastin aloen was FDA Apporved ... Read on »

Apheresis for hypercholestrolemia by Mark Levin Posted in: Blog Posts in Cancer In the United States, LDL apheresis is approved for homozygous familial hypercholestrolemia (FH) patients with an LDL cholesterol level ≥ 500 mg/dL. For patients with heter ... Read on »

Temodar and rituximab for primary CNS lymphoma by Mark Levin Posted in: Blog Posts in Cancer The story of temazolomide for primary CNS lymphhoma starts in 2000, when the first case report ot its use was published. This patient with primary brain lymphoma who has been ... Read on »

Screening for malignancy for DVT by Mark Levin Posted in: Blog Posts in Cancer There seems to be no indication ofr chest MRI. There are no clincal findigns or potential diagnoses that would invovle the chest and need to be excluded. A search for malignan ... Read on »

Neutron Beam Radiotherapy by Mark Levin Posted in: Blog Posts in Cancer Neutron beam therapy is a specialized form of external beam radiation therapy. It is often used to treat inoperable tumors or tumors that are radioresistant, meaning that they ... Read on »

Testosterone replacement after prostatectomy for prostae cancer by Mark Levin Posted in: Blog Posts in Cancer It is generally thought that prostate cacner is an absolute contraindication for testosterone therapy, as recommended by the WHO from the Third International Consensus Consult ... Read on »

Erbitux first line by Mark Levin Posted in: Blog Posts in Cancer One of the major recent advances in the field of colorectal cancer has been the identification of K-Ras mutations. K-Ras mutation determines colorectal cacner's responsiveness ... Read on »

Leukine for prostate cancer by Mark Levin Posted in: Blog Posts in Cancer Granulocyte macrophage colony-stimulating factor is a pleiotropic cytokine capable of inducing systemic immune responses against experimental and human tumors. GM-CSF stimulat ... Read on »

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