For the past 30 years Dr. Alan MacDonald has worked to revive the Model of Syphilis and draw attention to clinical and laboratory parallels between Treponema pallidum infection and Lyme Borreliosis. Dr. MacDonald hypothesized that Alzheimer's disease might be the late neural borreliosis equivalent of General paresis of the insane. He further hypothesized that syphilitic Tabes Dorsalis might have a "spinal cord only" neurodegenerative equivalent In borreliosis, namely Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease). He hypothesized that syphilitic Temporal arteritis might have a Borrelia equivalent in Temporal arteritis of unknown cause. In addition to the ongoing Alzheimer's studies, which would occupy the remainder of his research career, Alan made basic new observations in pathobiology. He was the first to publish evidence for a cystic form of Bb, granular forms of Bb, and cell wall deficient forms. Although officially retired now, Dr. MacDonald has started a research collaboration with Dr. Eva Sapi of University of New Haven.
Dr MacDonald and many other distinguished researchers and doctors will be presenting at this years ILADS Conference in Boston details here Dr MacDonald's hypothesis are slowly becoming acknowledged and researched elsewhere we have a lot to thank him for. Judith Miklossy has also found Borrelia in the brains of patients with Alzheimer's here Dr Martz found patients with ALS linked to Borrelia and with appropriate antibiotics some recovered and some stabalised here
Three cases of neuroborreliosis misdiagnosed as giant cell arteritis. here Link to Dr MacDonald's website here link to Borreliosis Spirochetes imaged from Human Blood -- Case studies here