Discovering how lupus attacks the brain. Researchers uncovered how the lupus immune system attacks the central nervous system (CNS), leading to current work on a new targeted treatment for neurological and psychological complications of lupus. Researcher: Betty Diamond, MD
Discovering how lupus harms the heart. A chemically altered form of ‘good’ cholesterol was found to contribute to circulatory system damage in lupus. This discovery led to new ways to identify and treat patients at risk of heart disease. Researcher: Bevra Hahn, MD
Transforming kidney diagnosis. Researchers devised new non-invasive tests to diagnose and guide treatment of lupus kidney disease as alternatives to surgical kidney biopsies. Researchers: Chandra Mohan, MD, PhD ; Chaim Putterman, MD ; Joshua Thurman, MD
Discovering new genes. Genetic breakthroughs uncovered new culprits in lupus – the Toll-like receptors. Drugs that inhibit these proteins are soon to be tested in lupus patients. Researchers: Silvia Bolland, PhD and Ian R. Rifkin, MD, PhD
Smarter drug delivery. Using innovative nanotechnology to deliver drug doses directly to disease-causing cells promises to make existing lupus treatments safer and more effective. Researcher: Tarek Fahmy, PhD
Three cheers for the dedicated men and women doing their best to find a better way to treat, manage and diagnose lupus. Here's hoping for even more headway in the coming year!