Last week on World Kidney Day, the London Acute Kidney Injury Network was launched at the Welcome Foundation. Michael Wise told the audience about his experiences and feelings during a severe episode of AKI that followed on from a toxic shock type illness. AKI stage 3, requiring renal replacement therapy (RRT) is not a rare condition; it affects about 1% of hospitalized patients and has a mortality approaching 30%. Michael’s kidney function did not recover, he went on to develop end stage kidney disease and he has been on RRT since he was admitted to University College Hospital London in extremis at the beginning of the illness a few years ago. From Michaels account, it seems that the clinical staffs were expecting recovery of kidney function although Michael himself was not surprised when told that the kidney biopsy performed 6 months after the acute illness showed irreversible fibrosis. At that time, Michael was only passing at most a few hundred mls of urine a day.  He knew his own body. From there the story Michael tells is really a typical dialysis story. Even the way Michael started dialysis is not that unusual. Over the last decade or so starting dialysis in an unplanned fashion or as an  emergency  has fallen from over 30% to under 20 % ; in some  places were the links between primary and secondary care are strong , where kidney disease management programmes are in place or  where care is better integrated and coordinated  by GP practices , Kidney Care teams and Biochemistry laboratories being  connected by IT commencing dialysis in an unplanned way has fallen to between 5 to 7% . Back to Michael – he went onto satellite haemodialysis; he found it very difficult to maintain his work, had problems with sexual dysfunction and was still experiencing some of the sensory loss and distortions from his time on the intensive care unit. Coronary artery stenting was needed prior to transplant listing and disappointingly, immediate family members were blood group or tissue type unsuitable as live related donors. Michael’s, wife’s niece came forward, was suitable and gave Michael the gift of life by donating one of her kidneys. Michael’s new kidney   worked extremely well from the outset. Following recovery from the operation, Michael himself feels his overall functioning has now increased to about 75% of the level it was before he became unwell.   Last year there were 1,061 live donor kidney transplants, more live donors than deceased donors, despite the fact that year we saw the highest ever number of deceased organ donors in the UK – 959, a 7% increase compared to the previous 12 months; so Michaels narrative was a very fitting story for World Kidney Day 2012’s theme of kidney  transplantation.