Gout is a disorder that results from deposits of uric acid crystals, which accumulate in the joints because of high blood levels of uric acid (hyperuricemia).Although the joints are the most commonly affected part of the body, urate crystals can form in the kidney or other parts of the urinary system, where they can occasionally impair kidney function or cause.Gout is more common among men than women,and is particularly common in people older than 65 regardless of gender.
The kidney stones composed of uric acid that are part of gout often contain calcium crystals as well.Normally, uric acid, a by-product of cell nucleic acid breakdown, is present in small amounts in the blood because the body continually breaks down cells and forms new cells.Most often, the uric acid level in the blood becomes abnormally high when the kidneys cannot eliminate enough uric acid in the urine.Less commonly, gout may be caused by an identifiable underlying disorder and is then called secondary gout.High levels of uric acid in the blood often lead to high levels of uric acid in the joints.Sudden severe attacks of gout (called acute gouty arthritis) can occur without warning.
Podagra, recurrent instep inflammation, and a history of previous attacks that began suddenly and resolved spontaneously also suggest the diagnosis.Pain and inflammation initially involving one joint at a time, especially the joint at the base of the large toe.The diagnosis is usually confirmed when needle-shaped uric acid crystals are identified in a sample of a tophus or in joint fluid removed with a needle (joint aspiration) and viewed under a microscope with polarized light.A blood test showing high levels of urate (most accurate for diagnosis after an acute flare resolves).X-rays may show joint damage and the presence of tophi (uric acid crystal tophi that displace bone and produce cysts).Complete resolution of symptoms between attacks.
One:Colchicine is the traditional, but no longer the most common, first-step treatment.
Two:There’s excellent evidence of gout being relieved by black cherry.
Three:Nonsteroidal anti-inflammatory drugs (NSAIDs) are often effective in relieving pain and swelling in the joint (see see Nonsteroidal Anti-Inflammatory Drugs ).
Four:Corticosteroids — Antiinflammatory steroids, also known more properly as glucocorticoids, are effective agents for treating acute gout flares.
Five:Manuka oil, or Leptospermum scoparium, comes from the leaves of a bush that grows in New Zealand .