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What could cause your stomach to be very hard and painful?

Sometimes my stomach gets very hard and painful and there is a lump that sticks out.  I also have an enlarged spleen.  Any ideas?  

What would cause a reaction from lymph nodes and be found microscopically on a cat scan?

My doc said that something was causing my lymph nodes to react to it and that there was something was found in a cat scan I was just trying to get...
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